Zheng ZJ, Zhang S, Cao Y, Pu GC, Liu H. Collagenous nodule mixed simple cyst and hemangioma coexistence in the liver. World J Gastroenterol 2015; 21(14): 4419-4422 [PMID: 25892897 DOI: 10.3748/wjg.v21.i14.4419]
Corresponding Author of This Article
Shu Zhang, PhD, Department of General Surgery, The Third People’s Hospital of Chengdu, The Second Affiliated Hospital of Chengdu, Chongqing Medical University, 82 Qinglong Street, Chengdu 610031, Sichuan Province, China. zhangshu_1961@sina.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Apr 14, 2015; 21(14): 4419-4422 Published online Apr 14, 2015. doi: 10.3748/wjg.v21.i14.4419
Collagenous nodule mixed simple cyst and hemangioma coexistence in the liver
Zhen-Jiang Zheng, Shu Zhang, Yang Cao, Guang-Chun Pu, Hong Liu
Zhen-Jiang Zheng, Shu Zhang, Yang Cao, Guang-Chun Pu, Department of General Surgery, The Third People’s Hospital of Chengdu, The Second Affiliated Hospital of Chengdu, Chongqing Medical University, Chengdu 610031, Sichuan Province, China
Hong Liu, Department of Radiology, The Third People’s Hospital of Chengdu, The Second Affiliated Hospital of Chengdu, Chongqing Medical University, Chengdu 610031, Sichuan Province, China
Author contributions: Zhang S, Cao Y and Pu GC performed the surgery; Liu H collected the radiographic images; Zheng ZJ prepared the figures and drafted the manuscript; Zhang S revised the manuscript; all authors read and approved the final manuscript.
Ethics approval: The study was reviewed and approved by the Third People’s Hospital of Chengdu Institutional Review Board.
Informed consent: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest: There is no conflict of interest related to the manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Shu Zhang, PhD, Department of General Surgery, The Third People’s Hospital of Chengdu, The Second Affiliated Hospital of Chengdu, Chongqing Medical University, 82 Qinglong Street, Chengdu 610031, Sichuan Province, China. zhangshu_1961@sina.com
Telephone: +86-28-61318737 Fax: +86-28-61318736
Received: October 27, 2014 Peer-review started: October 28, 2014 First decision: November 14, 2014 Revised: December 14, 2014 Accepted: January 30, 2015 Article in press: January 30, 2015 Published online: April 14, 2015 Processing time: 170 Days and 10.4 Hours
Abstract
A 20-year-old female patient presented with two masses located in the left liver. In this patient, a computed tomography (CT) scan revealed a hypodense mass and a second well-defined mass with a calcified nodule in the left hepatic lobe. No enhancements were apparent in or around the masses. A laparotomy was performed due to the patient’s symptoms, namely, the atypical CT findings and a risk of rupture of the subcapsular lesion. The operation revealed two masses in the left hepatic lobe and a left liver resection was subsequently performed. One of the masses involved segment III and the other mass was located in segment IV. The histopathologic findings supported a diagnosis of collagenous nodule mixed simple cyst and hemangioma. A diagnosis of collagenous nodule mixed simple hepatic cyst is extremely rare and radiologically mimics a teratoma, hepatolithiasis, parasitic cyst, or hemangioma. Although hepatic hemangiomas are the most common benign tumors found in the liver, the present case showed atypical radiographic features.
Core tip: This case represents a rare presentation of a patient with multiple liver masses. A definitive diagnosis depends on the histopathologic findings. Collagenous nodules are a rare clinicopathologic finding in the liver. This paper discusses the pathogenesis of a collagenous nodule found in the liver. Although hepatic hemangiomas are the most common benign tumor in the liver, this case showed atypical radiographic features.
