Case Report
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 14, 2015; 21(10): 3139-3145
Published online Mar 14, 2015. doi: 10.3748/wjg.v21.i10.3139
Eosinophilic gastroenteritis associated with eosinophilic cystitis: Computed tomography and magnetic resonance imaging findings
Shu-Gao Han, Ying Chen, Zi-Hua Qian, Li Yang, Ri-Sheng Yu, Xiu-Liang Zhu, Qing-Hai Li, Qian Chen
Shu-Gao Han, Ying Chen, Zi-Hua Qian, Li Yang, Ri-Sheng Yu, Xiu-Liang Zhu, Qing-Hai Li, Department of Radiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
Qian Chen, Department of Pathology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
Author contributions: Yu RS designed the study; Han SG acquired and analyzed the data and drafted the manuscript; Chen Y, Qian ZH, Yang L, Zhu XL and Li QH analyzed the clinical and imaging data; Chen Q analyzed and interpreted the pathological data; all authors participated in the editing and have read and approved the final manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ri-Sheng Yu, MD, Department of Radiology, Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China. cjr.yurisheng@vip.163.com
Telephone: +86-571-87783924 Fax: +86-571-87784556
Received: July 21, 2014
Peer-review started: July 24, 2014
First decision: September 27, 2014
Revised: November 7, 2014
Accepted: December 20, 2014
Article in press: December 22, 2014
Published online: March 14, 2015
Processing time: 237 Days and 21.9 Hours
Abstract

Eosinophilic gastroenteritis (EG) is a rare, distinct clinical entity, and EG associated with eosinophilic cystitis (EC) is extremely rare and has not been well documented. Here, we report two cases of EG and coexistent EC along with findings from computed tomography (CT) and magnetic resonance imaging (MRI). An 18-year-old male with a history of hematuria, urgency and occasional urodynia for two weeks and a 34-year-old male with a history of abdominal distention for one week were admitted to our hospital. Abdominal contrast-enhanced CT in both patients revealed wall thickening in different parts of the gastrointestinal tract with inhomogeneous reinforcement, coexistent with local or diffuse bladder wall thickening with progressive enhancement, and also showed that the bladder mucosal lining was nondestructive. Pelvic MRI showed that the local or diffuse thickened bladder wall was iso-intense on T1-weighted images, hypo-intense on T2-weighted images, and slightly restricted on diffusion weighted imaging (DWI) in one case. After therapy, the thickened wall of the gastrointestinal tract and urinary bladder had improved markedly in the two cases. To the best of our knowledge, this is the first report on the radiological imaging of EG and coexistent EC by both CT and MRI and the first with DWI findings.

Keywords: Eosinophilic gastroenteritis; Eosinophilic cystitis; Computed tomography; Magnetic resonance imaging; Diffusion weighted imaging

Core tip: This article reports two rare cases of eosinophilic gastroenteritis (EG) and coexistent eosinophilic cystitis (EC) with findings from computed tomography (CT) and magnetic resonance imaging (MRI), which have not previously been documented in detail. To the best of our knowledge, this is the first report on EG and coexistent EC with examinations by both CT and MRI, as well as the first one with diffusion-weighted imaging findings.