Case Report
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World J Gastroenterol. Apr 14, 2014; 20(14): 4102-4105
Published online Apr 14, 2014. doi: 10.3748/wjg.v20.i14.4102
Simultaneous liver mucinous cystic and intraductal papillary mucinous neoplasms of the bile duct: A case report
Agnieszka Budzynska, Marek Hartleb, Ewa Nowakowska-Dulawa, Robert Krol, Piotr Remiszewski, Michal Mazurkiewicz
Agnieszka Budzynska, Marek Hartleb, Ewa Nowakowska-Dulawa, Department of Gastroenterology and Hepatology, Medical University of Silesia, 40-752 Katowice, Poland
Robert Krol, Department of General, Vascular and Transplant Surgery, Medical University of Silesia, 40-027 Katowice, Poland
Piotr Remiszewski, Department of General, Transplant and Liver Surgery, Medical University of Warsaw, 02-097 Warsaw, Poland
Michal Mazurkiewicz, Department of Pathological Anatomy, Medical University of Warsaw, 02-004 Warsaw, Poland
Author contributions: Budzynska A and Hartleb M designed the report; Budzynska A, Hartleb M, Nowakowska-Dulawa E, Krol R and Remiszewski P were attending doctors for the patient; Remiszewski P performed the surgery, Mazurkiewicz M performed pathological examinations; Budzynska A organized the report and wrote the paper; Hartleb M revised the paper critically for intellectual content.
Correspondence to: Agnieszka Budzyńska, MD, Department of Gastroenterology and Hepatology, Medical University of Silesia, Medykow 14, 40-752 Katowice, Poland. budzynskaagnieszka@poczta.onet.pl
Telephone: +48-32-7894401 Fax: +48-32-7894402
Received: April 29, 2013
Revised: September 14, 2013
Accepted: October 17, 2013
Published online: April 14, 2014
Processing time: 350 Days and 5.7 Hours
Abstract

Cystic hepatic neoplasms are rare tumors, and are classified into two separate entities: mucinous cystic neoplasms (MCNs) and intraductal papillary mucinous neoplasms of the bile duct (IPMN-B). We report the case of a 56-year-old woman who presented with abdominal pain and jaundice due to the presence of a large hepatic multilocular cystic tumor associated with an intraductal tumor. Partial hepatectomy with resection of extrahepatic bile ducts demonstrated an intrahepatic MCN and an intraductal IPMN-B. This is the first report of the simultaneous occurrence of these two histologically distinct entities in the liver.

Keywords: Liver; Mucinous cystic neoplasm; Intraductal papillary mucinous neoplasm of the bile duct

Core tip: Cystic hepatic neoplasms are rare tumors, and are classified as mucinous cystic neoplasms (MCN) characterized by intracystic septae, ovarian-like stroma, and no communication with bile ducts; and intraductal papillary mucinous neoplasms of the bile duct (IPMN-B) characterized by intraductal growth, dilated bile ducts, and papillary projections. We report a 56-year-old woman diagnosed with a large multilocular cystic tumor in the liver and in dilated extrahepatic bile ducts that were two histologically distinct cystic tumors. This is the first report of the simultaneous occurrence of MCN and IPMN-B. We present diagnostic considerations, therapeutic approaches, and the prognosis of cystic tumors of the liver.