Published online Dec 15, 1996. doi: 10.3748/wjg.v2.i4.230
Revised: August 8, 1996
Accepted: August 23, 1996
Published online: December 15, 1996
AIM: To analyse the correlation between HDV infection and HBV serum markers.
METHODS: Patients who were positive for HBV serum markers were selected and HDV infection was examined in them. Blood donors were used as a control group. Both HDV infection and HBV serum markers were tested by enzyme-linked immunosorbent assay.
RESULTS: HDV infection was detected in 40 of 289 patients who were positive for HBV serum markers. The overall positive rate of HDV infection was 13.8%. The positive rates of HDV infection in HBsAg(+) group, HBcAb(+) group and HBeAb(+) group were 17.6%, 18.8% and 25.2%, respectively, which were higher than that in HBeAg(+) group (10.9%), and none was detected in HBsAb(+) group. HDV infection appeared in HBsAg(+)HBcAb(+)HBeAb(+) patients with a positive rate of 26.2%, which was much higher than that in HBsAg(+)HBcAb(+)HBeAg(+) patients (10.9%).
CONCLUSION: HDV coinfection is more frequent in HBsAg(+) HBcAb(+)HBeAb(+) patients than in BsAg(+)HBcAb(+)HBeAg(+) patients. HDV infection is not completely related with the speed and amount of HBV replication.