Ahn SY, Park SY, Kweon YO, Tak WY, Bae HI, Cho SH. Successful treatment of multiple hepatocellular adenomas with percutaneous radiofrequency ablation. World J Gastroenterol 2013; 19(42): 7480-7486 [PMID: 24259982 DOI: 10.3748/wjg.v19.i42.7480]
Corresponding Author of This Article
Soo Young Park, MD, PhD, Department of Internal Medicine, Kyungpook National University Hospital, Samduk 2-50, Junggu, Daegu 700-721, South Korea. psyoung0419@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Nov 14, 2013; 19(42): 7480-7486 Published online Nov 14, 2013. doi: 10.3748/wjg.v19.i42.7480
Successful treatment of multiple hepatocellular adenomas with percutaneous radiofrequency ablation
Sun Young Ahn, Soo Young Park, Young Oh Kweon, Won Young Tak, Han Ik Bae, Seung Hyun Cho
Sun Young Ahn, Soo Young Park, Young Oh Kweon, Won Young Tak, Department of Internal Medicine, Kyungpook National University Hospital, Daegu 700-721, South Korea
Han Ik Bae, Department of Pathology, Kyungpook National University Hospital, Daegu 700-721, South Korea
Seung Hyun Cho, Department of Radiology, Kyungpook National University Hospital, Daegu 700-721, South Korea
Author contributions: Ahn SY, Kweon YO, Tak WY and Park SY designed this article and discussed the clinical features; Bae HI performed pathological examinations; Cho SH performed image diagnosis; Ahn SY wrote the paper; Park SY revised this article critically for important intellectual content.
Correspondence to: Soo Young Park, MD, PhD, Department of Internal Medicine, Kyungpook National University Hospital, Samduk 2-50, Junggu, Daegu 700-721, South Korea. psyoung0419@gmail.com
Telephone: +82-53-2005516 Fax: +82-53-4268773
Received: July 25, 2013 Revised: September 5, 2013 Accepted: September 15, 2013 Published online: November 14, 2013 Processing time: 116 Days and 2.8 Hours
Abstract
Hepatocellular adenoma (HCA) is one of the important complications of glycogen storage disease type Ia (GSD-Ia) because it can be transformed into hepatocellular carcinoma. Although surgical resection is a standard treatment of choice for solitary HCA, multiple HCAs in GSD-Ia patients present as therapeutic challenges for curative treatment. Therefore, treatment strategy according to malignant potential is important in management of HCAs in GSD-Ia. The authors present a case of histologically proven multiple HCAs without β-catenin mutations occurred in a GSD-Ia patient treated successfully with percutaneous radiofrequency ablation as a minimally invasive therapy.
Core tip: Risk stratification by pathological examination is an important step in deciding therapeutic options of multiple hepatocellular adenoma in glycogen storage disease type Ia patients.
