Mori H, Kobara H, Rafiq K, Nishiyama N, Fujihara S, Ayagi M, Yachida T, Kato K, Masaki T. Radical excision of Barrett's esophagus and complete recovery of normal squamous epithelium. World J Gastroenterol 2013; 19(31): 5195-5198 [PMID: 23964158 DOI: 10.3748/wjg.v19.i31.5195]
Corresponding Author of This Article
Hirohito Mori, MD, PhD, Department of Gastroenterology and Neurology, Kagawa University, 1750-1 Ikenobe, Miki, Kita, Kagawa 761-0793, Japan. hiro4884@med.kagawa-u.ac.jp
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Hirohito Mori, Hideki Kobara, Noriko Nishiyama, Shintaro Fujihara, Maki Ayagi, Tatsuo Yachida, Kiyohito Kato, Tsutomu Masaki, Department of Gastroenterology and Neurology, Kagawa University, Kagawa 761-0793, Japan
Kazi Rafiq, Department of Pharmacology, Kagawa University, Kagawa 761-0793, Japan
Author contributions: Mori H conceived the research and drafted the article; Rafiq K, Fujihara S, Nishiyama N, Ayagi M, Yachida T, Kato K, and Kobara H participated equally in the work; Masaki T provided critical revision of the manuscript for intellectual content and was responsible for final approval of the manuscript.
Correspondence to: Hirohito Mori, MD, PhD, Department of Gastroenterology and Neurology, Kagawa University, 1750-1 Ikenobe, Miki, Kita, Kagawa 761-0793, Japan. hiro4884@med.kagawa-u.ac.jp
Telephone: +81-87-8912156 Fax: +81-87-8912158
Received: May 16, 2013 Revised: June 18, 2013 Accepted: July 4, 2013 Published online: August 21, 2013 Processing time: 94 Days and 19.2 Hours
Abstract
To treat Barrett’s esophagus (BE), radiofrequency ablation or cryotherapy are effective treatments for eradicating BE with dysplasia and intestinal metaplasia, and reduce the rates of Barrett’s esophageal adenocarcinoma (BAC). However, patients with BE and dysplasia or early cancer who achieved complete eradication of intestinal metaplasia, BE recurred in 5% within a year, requiring expensive endoscopic surveillances. We performed endoscopic submucosal dissection as complete radically curable treatment procedure for BE with dysplasia, intestinal metaplasia and BAC.
Core tip: Radiofrequency ablation or cryotherapy is effective for eradicating Barrett’s esophagus (BE) with dysplasia; however, it recurs in 5% in a year. Endoscopic submucosal dissection is a complete radically curable treatment procedure for BE with dysplasia and Barrett’s esophageal adenocarcinoma.
