Brief Article
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World J Gastroenterol. Jan 21, 2013; 19(3): 394-398
Published online Jan 21, 2013. doi: 10.3748/wjg.v19.i3.394
Single-incision vs three-port laparoscopic cholecystectomy: Prospective randomized study
Ming-Xin Pan, Ze-Sheng Jiang, Yuan Cheng, Xiao-Ping Xu, Zhi Zhang, Jia-Sheng Qin, Guo-Lin He, Ting-Cheng Xu, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao
Ming-Xin Pan, Ze-Sheng Jiang, Yuan Cheng, Xiao-Ping Xu, Zhi Zhang, Jia-Sheng Qin, Guo-Lin He, Ting-Cheng Xu, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao, Second Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China
Author contributions: Pan MX, Jiang ZS and Cheng Y contributed equally to this work; Pan MX and Gao Y designed the trial; Pan MX, Jiang ZS, Xu XP, Zhang Z, Qin JS, He GL, Xu TC, Zhou CJ and Liu HY performed the surgery; Pan MX and Cheng Y revised the paper.
Correspondence to: Yi Gao, MD, Second Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, No. 253, Gongye Avenue, Haizhu District, Guangzhou 510282, Guangdong Province, China. gaoyi6146@163.com
Telephone: +86-20-61643207 Fax: +86-20-84318988
Received: September 27, 2012
Revised: November 23, 2012
Accepted: December 15, 2012
Published online: January 21, 2013
Processing time: 116 Days and 19.6 Hours
Abstract

AIM: To compare the clinical outcome of single-incision laparoscopic cholecystectomy (SILC) with three-port laparoscopic cholecystectomy (TPLC).

METHODS: Between 2009 and 2011, one hundred and two patients with symptomatic benign gallbladder diseases were randomized to SILC (n = 49) or TPLC (n = 53). The primary end point was post operative pain score (at 6 h and 7 d). Secondary end points were blood loss, operation duration, overall complications, postoperative analgesic requirements, length of hospital stay, cosmetic result and total cost. Surgical techniques were standardized and all operations were performed by one experienced surgeon, who had performed more than 500 laparoscopic cholecystectomies.

RESULTS: One patient in the SILC group required conversion to two-port LC. There were no open conversions or major complications in either treatment groups. There were no differences in terms of estimated blood loss (mean ± SD, 14 ± 6.0 mL vs 15 ± 4.0 mL), operation duration (mean ± SD, 41.8 ± 17.0 min vs 38.5 ± 22.0 min), port-site complications (contusion at incision: 5 cases vs 4 cases and hematoma at incision: 2 cases vs 1 case), total cost (mean ± SD, 12 075 ± 1047 RMB vs 11 982 ± 1153 RMB) and hospital stay (mean ± SD, 1.0 ± 0.5 d vs 1.0 ± 0.2 d) , respectively. TPLC had a significantly worse visual analogue pain score at 8 h after surgery (mean ± SD, 3.5 ± 1.6 vs 2.0 ± 1.5), however, the scores were similar on day 7 (mean ± SD, 2.5 ± 1.4 vs 2.0 ± 1.3). Cosmetic satisfaction, as determined by a survey at 2 mo follow-up favored SILC (mean ± SD, 8 ± 0.4 vs 6 ± 0.2).

CONCLUSION: SILC is a safe and feasible approach in selected patients. The main advantages are a better cosmetic result and less pain.

Keywords: Cholecystectomy; Laparoscopic; Single-incision; Randomized; Laparoscopic cholecystectomy