Tari A, Asaoku H, Kunihiro M, Tanaka S, Yoshino T. Usefulness of positron emission tomography in primary intestinal follicular lymphoma. World J Gastroenterol 2013; 19(12): 1992-1996 [PMID: 23569346 DOI: 10.3748/wjg.v19.i12.1992]
Corresponding Author of This Article
Dr. Akira Tari, Division of Gastroenterology, Department of Internal Medicine, Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital, 1-9-6 Senda-machi, Naka-ku, Hiroshima 734-8551, Japan. stomach2@hiroshima-med.jrc.or.jp
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Akira Tari, Masaki Kunihiro, Division of Gastroenterology, Department of Internal Medicine, Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital, Hiroshima 734-8551, Japan
Hideki Asaoku, Department of Clinical Laboratory, Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital, Hiroshima 734-8551, Japan
Shinji Tanaka, Department of Endoscopy, Hiroshima University Hospital, Hiroshima 734-8551, Japan
Tadashi Yoshino, Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8530, Japan
Author contributions: Tari A performed the endoscopic examination, diagnosed and decided treatment policy, analyzed the data and wrote the paper; Asaoku H performed the hematological examination, diagnosed and decided treatment policy; Kunihiro M performed the endoscopic examination and diagnosis; Tanaka S performed the double-balloon enteroscopy and diagnosis; and Yoshino T performed the pathological diagnosis.
Correspondence to: Dr. Akira Tari, Division of Gastroenterology, Department of Internal Medicine, Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital, 1-9-6 Senda-machi, Naka-ku, Hiroshima 734-8551, Japan. stomach2@hiroshima-med.jrc.or.jp
Telephone: +81-82-2413111 Fax: +81-82-2460676
Received: November 20, 2012 Revised: December 25, 2012 Accepted: January 5, 2013 Published online: March 28, 2013 Processing time: 129 Days and 18.7 Hours
Abstract
Double-balloon enteroscopy (DBE) and video capsule endoscopy are useful for the diagnosis of lymphoma in the small intestine. However, DBE cannot be safely performed in cases with passage disturbance due to wall thickening and stenosis. Additionally, video capsule endoscopy cannot be performed in such cases because of the risk of retention. Here, we report 4 cases of primary follicular lymphoma of the gastrointestinal tract that could be detected using 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography (PET-CT). The endoscopic findings of these 4 cases included lesions with wall thickening, which comprised macroscopically clusters of nodules, dense clusters of whitish granules or small nodules, fold thickening and ulcers with irregular margins that occupied the whole lumen with edematous mucosa. All patients fulfilled the World Health Organization grade 1 criteria. 18F-fluorodeoxyglucose PET-CT can help predict the risks that may result from certain endoscopic examinations, such as DBE and video capsule endoscopy.