Brief Article
Copyright ©2011 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Feb 7, 2011; 17(5): 671-676
Published online Feb 7, 2011. doi: 10.3748/wjg.v17.i5.671
Fast-track rehabilitation program vs conventional care after colorectal resection: A randomized clinical trial
Gang Wang, Zhi-Wei Jiang, Jing Xu, Jian-Feng Gong, Yang Bao, Li-Fei Xie, Jie-Shou Li
Gang Wang, Zhi-Wei Jiang, Jian-Feng Gong, Yang Bao, Li-Fei Xie, Jie-Shou Li, Research Institute of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210002, Jiangsu Province, China
Jing Xu, Department of Medical Oncology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210002, Jiangsu Province, China
Author contributions: Wang G, Jiang ZW and Li JS designed the research; Wang G, Jiang ZW, Xu J, Gong JF, Bao Y and Xie LF performed the research; Wang G analyzed the data; Wang G and Xu J wrote the paper.
Supported by Social Development Fund of Jiangsu Province, No. BS2007054
Correspondence to: Zhi-Wei Jiang, MD, Research Institute of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, 305 Zhongshan East Road, Nanjing 210002, Jiangsu Province, China. surgery34@163.com
Telephone: +86-25-80860137 Fax: +86-25-84803956
Received: October 11, 2010
Revised: November 17, 2010
Accepted: November 24, 2010
Published online: February 7, 2011
Abstract

AIM: To compare the fast-track rehabilitation program and conventional care for patients after resection of colorectal cancer.

METHODS: One hundred and six consecutive patients who underwent fast-track rehabilitation program were encouraged to have early oral feeding and movement for early discharge, while 104 consecutive patients underwent conventional care after resection of colorectal cancer. Their gastrointestinal functions, postoperative complications and hospital stay time were recorded.

RESULTS: The restoration time of gastrointestinal functions in the patients was significantly faster after fast-track rehabilitation program than after conventional care (2.1 d vs 3.2 d, P < 0.01). The percentage of patients who developed complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care (13.2% vs 26.9%, P < 0.05). Also, the percentage of patients who had general complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care (6.6% vs 15.4%, P < 0.05). The postoperative hospital stay time of the patients was shorter after fast-track rehabilitation program than after conventional care (5 d vs 7 d, P < 0.01). No significant difference was observed in the re-admission rate 30 d after fast-track rehabilitation program and conventional care (3.8% vs 8.7%).

CONCLUSION: The fast-track rehabilitation program can significantly decrease the complications and shorten the time of postoperative hospital stay of patients after resection colorectal cancer.

Keywords: Perioperative care, Fast track, Rehabilitation, Colorectal cancer resection