Banks MR, Haidry R, Butt MA, Whitley L, Stein J, Langmead L, Bloom SL, O’Bichere A, McCartney S, Basherdas K, Rodriguez-Justo M, Lovat LB. High resolution colonoscopy in a bowel cancer screening program improves polyp detection. World J Gastroenterol 2011; 17(38): 4308-4313 [PMID: 22090787 DOI: 10.3748/wjg.v17.i38.4308]
Corresponding Author of This Article
Dr. Laurence B Lovat, Department of Gastrointestinal Services, University College London Hospitals NHS Foundation Trust, London NW1 2BU, United Kingdom. l.lovat@uclh.nhs.uk
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Brief Article
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World J Gastroenterol. Oct 14, 2011; 17(38): 4308-4313 Published online Oct 14, 2011. doi: 10.3748/wjg.v17.i38.4308
High resolution colonoscopy in a bowel cancer screening program improves polyp detection
Matthew R Banks, Rehan Haidry, M Adil Butt, Lisa Whitley, Judith Stein, Louise Langmead, Stuart L Bloom, Austin O’Bichere, Sara McCartney, Kalpesh Basherdas, Manuel Rodriguez-Justo, Laurence B Lovat
Matthew R Banks, Rehan Haidry, M Adil Butt, Lisa Whitley, Judith Stein, Louise Langmead, Stuart L Bloom, Austin O’Bichere, Sara McCartney, Kalpesh Basherdas, Laurence B Lovat, Department of Gastrointestinal Services, University College London Hospitals NHS Foundation Trust, London NW1 2BU, United Kingdom
Manuel Rodriguez-Justo, Department of Histopathology, University College London Hospitals NHS Foundation Trust, London NW1 2BU, United Kingdom
Author contributions: Banks MR and Lovat LB designed the study; Banks MR, Whitley L, Stein J, Langmead L, Bloom SL, O’Bichere A, McCartney S, Rodriguez-Justo M, and Basherdas K performed the research; Banks MR, Haidry R, Butt MA and Lovat LB wrote and edited the paper and related articles.
Supported by Proportion of UCLH/UCL funding from the Department of Health’s NIHR Biomedical Research Centres funding scheme; A grant from the UCL experimental cancer medicine centre; Unrestricted educational grant support from Pentax United Kingdom (Lovat LB)
Correspondence to: Dr. Laurence B Lovat, Department of Gastrointestinal Services, University College London Hospitals NHS Foundation Trust, London NW1 2BU, United Kingdom. l.lovat@uclh.nhs.uk
Telephone: +44-203-4567890 Fax: +44-207-8132828
Received: February 14, 2011 Revised: May 19, 2011 Accepted: May 26, 2011 Published online: October 14, 2011
Abstract
AIM: To compare high resolution colonoscopy (Olympus Lucera) with a megapixel high resolution system (Pentax HiLine) as an in-service evaluation.
METHODS: Polyp detection rates and measures of performance were collected for 269 colonoscopy procedures. Five colonoscopists conducted the study over a three month period, as part of the United Kingdom bowel cancer screening program.
RESULTS: There were no differences in procedure duration (χ2 P = 0.98), caecal intubation rates (χ2 P = 0.67), or depth of sedation (χ2 P = 0.64). Mild discomfort was more common in the Pentax group (χ2 P = 0.036). Adenoma detection rate was significantly higher in the Pentax group (χ2 test for trend P = 0.01). Most of the extra polyps detected were flat or sessile adenomas.
CONCLUSION: Megapixel definition colonoscopes improve adenoma detection without compromising other measures of endoscope performance. Increased polyp detection rates may improve future outcomes in bowel cancer screening programs.
