Kim MC, Kim CS, Chung TH, Park HO, Yoo CI. Metabolic syndrome, lifestyle risk factors, and distal colon adenoma: A retrospective cohort study. World J Gastroenterol 2011; 17(35): 4031-4037 [PMID: 22046093 DOI: 10.3748/wjg.v17.i35.4031]
Corresponding Author of This Article
Cheol-In Yoo, Professor, MD, PhD, Department of Occupational and Environmental Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, 290-3 Jeonha-dong, Dong-gu, Ulsan 682-714, South Korea. ciyoo@ulsan.ac.kr
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Brief Article
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World J Gastroenterol. Sep 21, 2011; 17(35): 4031-4037 Published online Sep 21, 2011. doi: 10.3748/wjg.v17.i35.4031
Metabolic syndrome, lifestyle risk factors, and distal colon adenoma: A retrospective cohort study
Moon-Chan Kim, Chang-Sup Kim, Tae-Heum Chung, Hyoung-Ouk Park, Cheol-In Yoo
Moon-Chan Kim, Chang-Sup Kim, Tae-Heum Chung, Department of Family Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 682-714, South Korea
Hyoung-Ouk Park, Cheol-In Yoo, Department of Occupational and Environmental Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 682-714, South Korea
Author contributions: Kim MC contributed to the concept of the study, analyzed the data and wrote the paper; Kim CS and Chung TH collected the data and wrote the paper; Park HO analyzed the data and wrote the paper; Yoo CI was the principal investigator, designed the study, analyzed the data and wrote the paper.
Supported by The Biomedical Research Center Promotion Fund of the Ulsan University Hospital (UUH-2008-08)
Correspondence to: Cheol-In Yoo, Professor, MD, PhD, Department of Occupational and Environmental Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, 290-3 Jeonha-dong, Dong-gu, Ulsan 682-714, South Korea. ciyoo@ulsan.ac.kr
Telephone: +82-52-2508819 Fax: +82-52-2507289
Received: December 26, 2010 Revised: May 19, 2011 Accepted: May 26, 2011 Published online: September 21, 2011
Abstract
AIM: To investigate relationships between colorectal adenoma incidence, metabolic syndrome (MS) components and lifestyle factors.
METHODS: We conducted a retrospective cohort study using data from individuals who had multiple sigmoidoscopies for colon cancer at the Health Promotion Center of Ulsan University Hospital in Korea from 1998 to 2007.
RESULTS: By multivariate analysis, the incidence of distal colon adenoma was increased by more than 1.76 times in individuals with at least one component of MS compared to those without a component of MS. After adjustment for age, gender, smoking, drinking, and physical exercise, only high body mass index (BMI) was significantly associated with the incidence of distal colon adenoma (Hazard ratio 1.66, 95% confidence interval 1.05-2.62).
CONCLUSION: Our results suggest that high BMI may increase the risk of colorectal adenoma in Korean adults.
