Brief Article
Copyright ©2011 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Jan 21, 2011; 17(3): 385-390
Published online Jan 21, 2011. doi: 10.3748/wjg.v17.i3.385
Management of patients with sphincter of Oddi dysfunction based on a new classification
Jia-Qing Gong, Jian-Dong Ren, Fu-Zhou Tian, Rui Jiang, Li-Jun Tang, Yong Pang
Jia-Qing Gong, Jian-Dong Ren, Fu-Zhou Tian, Li-Jun Tang, Yong Pang, Department of General Surgery, the People’s Liberation Army General Hospital of Chengdu Command, Chengdu 610083, Sicuan Province, China
Rui Jiang, Department of Radiology, General Hospital of Chengdu Command, Chengdu 610083, Sicuan Province, China
Author contributions: Gong JQ performed the research, analyzed the data and wrote the paper; Ren JD analyzed the data and wrote the paper; Tian FZ played a leading role in this research and designed the research; Jiang R, Tang LJ and Pang Y helped collect and analyze the data.
Supported by The Health and Medical Research Council of the People’s Liberation Army, China, No. 08Z012
Correspondence to: Fu-Zhou Tian, Professor, Department of General Surgery, the People’s Liberation Army General Hospital of Chengdu Command, Chengdu 610083, Sicuan Province, China. cdgjq123@yahoo.com
Telephone: +86-28-86570621 Fax: +86-28-86570351
Received: August 30, 2010
Revised: September 26, 2010
Accepted: October 3, 2010
Published online: January 21, 2011
Abstract

AIM: To propose a new classification system for sphincter of Oddi dysfunction (SOD) based on clinical data of patients.

METHODS: The clinical data of 305 SOD patients documented over the past decade at our center were analyzed retrospectively, and typical cases were reported.

RESULTS: The new classification with two more types (double-duct, biliary-pancreatic reflux) were set up on the basis of the Milwaukee criteria. There were 229 cases of biliary-type SOD, including 192 (83.8%) cases cured endoscopically, and 29 (12.7%) cured by open abdominal surgery, and the remaining 8 (3.5%) cases observed with unstable outcomes. Eight (50%) patients with pancreatic-type SOD were cured by endoscopic treatment, and the remaining 8 patients were cured after open abdominal surgery. There were 19 cases of double-duct-type SOD, which consisted of 7 (36.8%) patients who were cured endoscopically and 12 (63.2%) who were cured surgically. A total of 41 cases were diagnosed as biliary-pancreatic–reflux-type SOD. Twenty (48.8%) of them were treated endoscopically, 16 (39.0%) were treated by open abdominal surgery, and 5 (12.2%) were under observation.

CONCLUSION: The newly proposed SOD classification system introduced in this study better explains the clinical symptoms of SOD from the anatomical perspective and can guide clinical treatment of this disease.

Keywords: Sphincter of Oddi dysfunction; Classification; Diagnosis; Treatment