Emre A, Serin KR, Özden İ, Tekant Y, Bilge O, Alper A, Güllüoğlu M, Güven K. Intrahepatic biliary cystic neoplasms: Surgical results of 9 patients and literature review. World J Gastroenterol 2011; 17(3): 361-365 [PMID: 21253396 DOI: 10.3748/wjg.v17.i3.361]
Corresponding Author of This Article
Dr. Kürşat Rahmi Serin, Department of General Surgery, Hepatopancreatobiliary Surgery Unit, Istanbul Faculty of Medicine, Istanbul University, Millet Cad., Fatih, Istanbul 34093, Turkey. dr_krserin@yahoo.com
Article-Type of This Article
Brief Article
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Jan 21, 2011; 17(3): 361-365 Published online Jan 21, 2011. doi: 10.3748/wjg.v17.i3.361
Intrahepatic biliary cystic neoplasms: Surgical results of 9 patients and literature review
Ali Emre, Kürşat Rahmi Serin, İlgin Özden, Yaman Tekant, Orhan Bilge, Aydın Alper, Mine Güllüoğlu, Koray Güven
Ali Emre, Kürşat Rahmi Serin, İlgin Özden, Yaman Tekant, Orhan Bilge, Aydın Alper, Department of General Surgery, Hepatopancreatobiliary Surgery Unit, Istanbul Faculty of Medicine, Istanbul University, Istanbul 34093, Turkey
Mine Güllüoğlu, Department of Pathology, Istanbul Faculty of Medicine, Istanbul University, Istanbul 34093, Turkey
Koray Güven, Department of Radiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul 34093, Turkey
Author contributions: Emre A and Serin KR contributed equally to this work; Özden İ, Tekant Y, Bilge O and Alper A designed research, reviewed the literature and assisted in writing the paper; Güllüoğlu M analyzed the pathology specimens; Güven K reanalyzed the radiologic findings.
Correspondence to: Dr. Kürşat Rahmi Serin, Department of General Surgery, Hepatopancreatobiliary Surgery Unit, Istanbul Faculty of Medicine, Istanbul University, Millet Cad., Fatih, Istanbul 34093, Turkey. dr_krserin@yahoo.com
Telephone: +90-212-6211200 Fax: +90-212-6353082
Received: August 12, 2010 Revised: September 18, 2010 Accepted: September 26, 2010 Published online: January 21, 2011
Abstract
AIM: To investigate the eligible management of the cystic neplasms of the liver.
METHODS: The charts of 9 patients who underwent surgery for intrahepatic biliary cystic liver neoplasms between 2003 and 2008 were reviewed retrospectively. Informed consent was obtained from the patients and approval was obtained from the designated review board of the institution.
RESULTS: All patients were female with a median (range) age of 49 (27-60 years). The most frequent symptom was abdominal pain in 6 of the patients. Four patients had undergone previous laparotomy (with other diagnoses) which resulted in incomplete surgery or recurrences. Liver resection (n = 6) or enucleation (n = 3) was performed. The final diagnosis was intrahepatic biliary cystadenoma in 8 patients and cystadenocarcinoma in 1 patient. All symptoms resolved after surgery. There has been no recurrence during a median (range) 31 (7-72) mo of follow up.
CONCLUSION: In spite of the improvement in imaging modalities and increasing recognition of biliary cystadenoma and cystadenocarcinoma, accurate preoperative diagnosis may be difficult. Complete surgical removal (liver resection or enucleation) of these lesions yields satisfying long-term results.
