Kim HH, Hur YH, Koh YS, Cho CK, Kim JW. Intrahepatic biliary cystadenoma: Is there really an almost exclusively female predominance? World J Gastroenterol 2011; 17(25): 3073-3074 [PMID: 21799657 DOI: 10.3748/wjg.v17.i25.3073]
Corresponding Author of This Article
Young Hoe Hur, MD, Department of Surgery, Hepatobiliary and Pancreatic Tumor Clinic, Chonnam National University Hwasun Hospital, 160, Ilsim-ri, Hwasun-eup. Hwasun-gun, Jeollanam-do, 519-809, South Korea. surgihur@naver.com
Article-Type of This Article
Letters To The Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Jul 7, 2011; 17(25): 3073-3074 Published online Jul 7, 2011. doi: 10.3748/wjg.v17.i25.3073
Intrahepatic biliary cystadenoma: Is there really an almost exclusively female predominance?
Ho Hyun Kim, Young Hoe Hur, Yang Seok Koh, Chol Kyoon Cho, Jin Woong Kim
Ho Hyun Kim, Young Hoe Hur, Yang Seok Koh, Chol Kyoon Cho, Department of Surgery, Chonnam National University Medical School, 519-809 Gwangju, South Korea
Jin Woong Kim, Department of Radiology, Chonnam National University Medical School, 519-809 Gwangju, South Korea
Author contributions: Kim HH wrote the paper; Koh YS and Cho CK contributed equally to this work; Hur YH designed the research and supervised the paper; Kim JW performed a radiologic evaluation.
Correspondence to: Young Hoe Hur, MD, Department of Surgery, Hepatobiliary and Pancreatic Tumor Clinic, Chonnam National University Hwasun Hospital, 160, Ilsim-ri, Hwasun-eup. Hwasun-gun, Jeollanam-do, 519-809, South Korea. surgihur@naver.com
Telephone: +82-61-3797646 Fax: +82-61-3797661
Received: March 8, 2011 Revised: April 8, 2011 Accepted: April 15, 2011 Published online: July 7, 2011
Abstract
Biliary cystic tumors, such as cystadenomas and cystadenocarcinomas, are rare cystic tumors of the liver, accounting for less than 5% of all intrahepatic cysts of biliary origin. Biliary cystadenomas have been known to occur predominantly in women (> 85%), and 38%-44% of biliary cystadenocarcinomas have occurred in males. We wrote this letter to comment on a brief article (World J Gasteroenterol 2011 January 21; 17(3): 361-365) regarding a case of intrahepatic biliary cystic neoplasm treated with surgery. The adenoma-carcinoma sequence is the possible mechanism of carcinogenesis. If the carcinogenesis of biliary cystadenocarcinoma occurs in the adenoma-carcinoma sequence, we believe that the male-to-female ratio of cystadenoma should be higher than the incidence rate that has been reported to date.
