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World J Gastroenterol. May 21, 2011; 17(19): 2454-2454
Published online May 21, 2011. doi: 10.3748/wjg.v17.i19.2454
Published online May 21, 2011. doi: 10.3748/wjg.v17.i19.2454
Severe alcoholic hepatitis: Glucocorticoid saves lives and transplantation is promising
Alain Braillon, Gres, 27 rue Voiture, 80000 Amiens, France
Author contributions: Braillon A contributed all to the paper.
Correspondence to: Alain Braillon, MD, PhD, Gres, 27 rue Voiture, 80000 Amiens, France. braillon.alain@gmail.com
Telephone: +33-3-22955539
Received: November 23, 2010
Revised: February 15, 2011
Accepted: February 22, 2011
Published online: May 21, 2011
Revised: February 15, 2011
Accepted: February 22, 2011
Published online: May 21, 2011
Abstract
Glucocorticosteroids have been used as the only treatment for a long time which significantly reduced the mortality of the patients with severe alcoholic hepatitis. The efficacy of transplantation has been recently addressed in a pilot study. The result seems promising but needs larger multicenter trials.
Keywords: Alcoholic hepatitis; Glucocorticoids; Transplantation