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World J Gastroenterol. Apr 21, 2011; 17(15): 1939-1946
Published online Apr 21, 2011. doi: 10.3748/wjg.v17.i15.1939
Perianal Crohn’s disease: Is there something new?
Cesare Ruffolo, Marilisa Citton, Marco Scarpa, Imerio Angriman, Marco Massani, Ezio Caratozzolo, Nicolò Bassi
Cesare Ruffolo, Marco Massani, Ezio Caratozzolo, Nicolò Bassi, II Department of Surgery (IV unit), Regional Hospital Ca’ Foncello, 31100 Treviso, Italy
Marilisa Citton, Imerio Angriman, Department of Surgical and Gastroenterological Sciences, University of Padova, 35122 Padua Padova, Italy
Marco Scarpa, Department of Oncological Surgery, Veneto Oncological Institute, 35100 Padova, Italy
Author contributions: Ruffolo C and Citton M contributed equally to this paper; all authors contributed to conception and design, acquisition of data, draft and revision of the article and final approval of the version to be published.
Correspondence to: Cesare Ruffolo, MD, PhD, II Department of Surgery (IV unit), Regional Hospital Cà Foncello, Piazza Ospedale 1, 31100 Treviso, Italy. cruffolo@hotmail.com
Telephone: +39-422-322480 Fax: +39-422-322322
Received: December 1, 2010
Revised: January 17, 2011
Accepted: January 24, 2011
Published online: April 21, 2011

Perianal lesions are common in patients with Crohn’s disease, and display aggressive behavior in some cases. An accurate diagnosis is necessary for the optimal management of perianal lesions. Treatment of perianal Crohn’s disease includes medical and/or surgical options. Recent discoveries in the pathogenesis of this disease have led to advances in medical and surgical therapy with good results. Perianal lesions in Crohn’s disease remain a challenging aspect for both gastroenterologists and surgeons and lead to a greatly impaired quality of life for all patients affected by this disease. A multidisciplinary approach is mandatory to obtain the best results.

Keywords: Crohn disease, Diagnosis, Biologic therapy, Surgery, Rectal fistula