Brief Article
Copyright ©2011 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Apr 7, 2011; 17(13): 1766-1771
Published online Apr 7, 2011. doi: 10.3748/wjg.v17.i13.1766
EUS for choosing best endoscopic treatment of mesenchymal tumors of upper gastrointestinal tract
Xin-Xin Zhou, Feng Ji, Liang Xu, Lin Li, Yi-Peng Chen, Jing-Jing Lu, Chun-Wei Wang, Wei Huang
Xin-Xin Zhou, Feng Ji, Liang Xu, Lin Li, Yi-Peng Chen, Department of Gastroenterology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Jing-Jing Lu, Department of Gastroenterology, Beilun Zongrui Hospital, Ningbo 315806, Zhejiang Province, China
Chun-Wei Wang, Department of Gastroenterology, the Traditional Chinese Medicine Hospital of Ninghai, Ninghai 315600, Zhejiang Province, China
Wei Huang, Department of Gastroenterology, Jinhua Wenrong Hospital, Jinhua 321017, Zhejiang Province, China
Author contributions: Ji F and Zhou XX designed the research and wrote the paper; Ji F, Zhou XX, Xu L, Li L, Chen YP, Lu JJ, Wang CW and Huang W performed the research; Zhou XX and Xu L analyzed the data.
Correspondence to: Feng Ji, MD, PhD, Department of Gastroenterology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China. jifeng1126@sina.com
Telephone: +86-571-87236568 Fax: +86-571-87236611
Received: October 19, 2010
Revised: November 17, 2010
Accepted: November 24, 2010
Published online: April 7, 2011
Abstract

AIM: To evaluate the value of endoscopic ultrasonography (EUS) in the choice of endoscopic therapy strategies for mesenchymal tumors of the upper gastrointestinal tract.

METHODS: From July 2004 to September 2010, 1050 patients with upper gastrointestinal mesenchymal tumors (GIMTs) were diagnosed using EUS. Among them, 201 patients underwent different endoscopic therapies based on the deriving layers, growth patterns and lesion sizes.

RESULTS: Using EUS, we found 543 leiomyomas and 507 stromal tumors. One hundred and thirty-three leiomyomas and 24 stromal tumors were treated by snare electrosection, 6 leiomyomas and 20 stromal tumors were treated by endoloop, 10 stromal tumors were treated by endoscopic mucosal resection and 8 stromal tumors were treated by endoscopic submucosal dissection. Complete resection of the lesion was achieved in all cases. Of the mesenchymal tumors, 90.38% diagnosed by EUS were also identified by pathohistology. All wounds were closed up nicely and no recurrence was found in the follow-up after 2 mo.

CONCLUSION: EUS is an effective means of diagnosis for upper GIMTs and is an important tool in choosing the endoscopic therapy for GIMTs, by which the lesions can be treated safely and effectively.

Keywords: Leiomyoma, Stromal tumor, Endoscopic ultrasonography, Endoscopic therapy