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World J Gastroenterol. Apr 7, 2011; 17(13): 1690-1693
Published online Apr 7, 2011. doi: 10.3748/wjg.v17.i13.1690
Published online Apr 7, 2011. doi: 10.3748/wjg.v17.i13.1690
How to assess the severity of atrophic gastritis
Yan-Cheng Dai, Zhi-Peng Tang, Ya-Li Zhang, Department of Gastroenterology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
Yan-Cheng Dai, Zhi-Peng Tang, Ya-Li Zhang, The Institute of Digestive Disease Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
Author contributions: Dai YC, Tang ZP and Zhang YL contributed equally to this paper.
Supported by the Shanghai Leading Academic Discipline Project, No. J50305
Correspondence to: Zhi-Peng Tang, MD, Department of Gastroenterology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 725 South Wanpin Road, Shanghai 200032, China. zhipengtang@sohu.com
Telephone: +86-21-64385700 Fax: +86-21-64392310
Received: September 16, 2010
Revised: December 1, 2010
Accepted: December 8, 2010
Published online: April 7, 2011
Revised: December 1, 2010
Accepted: December 8, 2010
Published online: April 7, 2011
Abstract
Atrophic gastritis, is the main consequence of long-standing Helicobacter pylori infection, and is linked to the development of gastric cancer. The severity of atrophic gastritis is related to the lifetime risk of gastric cancer development, especially in terms of its degree and extent of mucosal damage. Therefore, it is important for clinicians to assess the severity of atrophic gastritis, interfere with the disease progress, and reverse gastric mucosal atrophy. In the article, we demonstrated some methods (conventional endoscopy, modern endoscopic technology and noninvasive methods) that may help assess the severity of atrophic gastritis and select the reasonable treatment protocols.
Keywords: Atrophic gastritis, Endoscopy, Pepsinogen