Case Report
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World J Gastroenterol. Feb 28, 2010; 16(8): 1039-1042
Published online Feb 28, 2010. doi: 10.3748/wjg.v16.i8.1039
Hepatic mucormycosis mimicking hilar cholangiocarcinoma: A case report and literature review
Ke-Wei Li, Tian-Fu Wen, Gan-Di Li
Ke-Wei Li, Tian-Fu Wen, Division of Liver Transplantation, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Gan-Di Li, Department of Pathology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Li KW and Wen TF contributed equally to this work; Li KW, Wen TF and Li GD performed research; Li KW and Wen TF wrote the paper.
Correspondence to: Tian-Fu Wen, PhD, Division of Liver Transplantation, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China. vivian522513@163.com
Telephone: +86-28-85513722 Fax: +86-28-85422411
Received: November 27, 2009
Revised: December 28, 2009
Accepted: January 4, 2010
Published online: February 28, 2010
Abstract

Mucormycosis is a rare but invasive opportunistic fungal infection associated with a high mortality rate, and normally occurs in immunocompromised patients. In this report, we describe an immunocompetent patient suffering from hepatic mucormycosis secondary to adrenal mucormycosis, which masquerades as hilar cholangiocarcinoma. After surgical procedure and treatment with amphotericin B and itraconazole, the patient recovered well and had a 2-year infection-free survival. To our knowledge, this special clinical manifestation of hepatic infection as well as adrenal mucormycosis has not been reported to date. Meanwhile, this is the first case of an immunocompetent patient with both adrenal and hepatic mucormycosis who has been treated successfully.

Keywords: Adrenal gland, Hilar cholangiocarcinoma, Liver, Mucormycosis