Liang TB, Liu Y, Bai XL, Yu J, Chen W. Sphincter of Oddi laxity: An important factor in hepatolithiasis. World J Gastroenterol 2010; 16(8): 1014-1018 [PMID: 20180243 DOI: 10.3748/wjg.v16.i8.1014]
Corresponding Author of This Article
Ting-Bo Liang, PhD, Department of Hepatobiliary and Pancreatic Surgery, Key Laboratory of Multi-Organ Transplantation of Ministry of Public Health, Key Laboratory of Organ Transplantation of Zhejiang Province, the First Affiliated Hospital, School of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. liangtingbo@zju.edu.cn
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Brief Article
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World J Gastroenterol. Feb 28, 2010; 16(8): 1014-1018 Published online Feb 28, 2010. doi: 10.3748/wjg.v16.i8.1014
Sphincter of Oddi laxity: An important factor in hepatolithiasis
Ting-Bo Liang, Yu Liu, Xue-Li Bai, Jun Yu, Wei Chen
Ting-Bo Liang, Yu Liu, Xue-Li Bai, Jun Yu, Wei Chen, Department of Hepatobiliary and Pancreatic Surgery, Key Laboratory of Multi-Organ Transplantation of Ministry of Public Health, Key Laboratory of Organ Transplantation of Zhejiang Province, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Liang TB designed the study and performed the majority of the work; Liu Y collected all the patients’ data and participated in the writing of the manuscript; Bai XL and Yu J answered for the follow-up of the patients; Chen W did the statistical treatment of the data.
Supported by Grants from National Natural Science Funds for Distinguished Young Scholars, No. 30925033; Science and Technology Planning Project of Zhejiang Province, China, No. 2007C24001
Correspondence to: Ting-Bo Liang, PhD, Department of Hepatobiliary and Pancreatic Surgery, Key Laboratory of Multi-Organ Transplantation of Ministry of Public Health, Key Laboratory of Organ Transplantation of Zhejiang Province, the First Affiliated Hospital, School of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. liangtingbo@zju.edu.cn
Telephone: +86-571-87236688 Fax: +86-571-87236688
Received: November 4, 2009 Revised: December 18, 2009 Accepted: December 25, 2009 Published online: February 28, 2010
Abstract
AIM: To evaluate the importance of sphincter of Oddi laxity (SOL) in hepatolithiasis (HL).
METHODS: Subjects included 98 patients diagnosed with HL between 2002 and 2007. Detailed histories were taken and the subjects were monitored until July 2008. HL patients were divided into two groups: Group I included 45 patients with SOL, and Group II included 53 patients without. Recurrence and reoperation indices of both groups were calculated and compared.
RESULTS: The recurrence index was 0.135 in Group I and 0.018 in Group II (P < 0.001). The reoperation index was 0.070 in Group I and 0.010 in Group II (P < 0.001). The mean frequency of biliary operation was 2.07 in Group I and 1.21 in Group II (P = 0.001). Differences between the two groups are significant.
CONCLUSION: HL patients with SOL tend to have a higher risk of recurrence and a larger demand for reoperation than those without this condition.
