Brief Article
Copyright ©2010 Baishideng. All rights reserved.
World J Gastroenterol. Feb 7, 2010; 16(5): 631-635
Published online Feb 7, 2010. doi: 10.3748/wjg.v16.i5.631
Clinical and endoscopic analysis of gastric Dieulafoy’s lesion
Yi-Juan Ding, Liang Zhao, Jun Liu, He-Sheng Luo
Yi-Juan Ding, Liang Zhao, Jun Liu, He-Sheng Luo, Department of Gastroenterology, Renmin Hospital of Wuhan University, Jiefang Road 238, Wuhan 430060, Hubei Province, China
Author contributions: Ding YJ and Luo HS designed the research; Ding YJ, Zhao L and Liu J performed the research; Ding YJ and Zhao L analyzed the data and wrote the paper.
Correspondence to: Liang Zhao, PhD, Department of Gastroenterology, Renmin Hospital of Wuhan University, Jiefang Road 238, Wuhan 430060, Hubei Province, China. airman-zhao@tom.com
Telephone: +86-27-88041911-82135 Fax: +86-27-88041911
Received: July 10, 2009
Revised: September 15, 2009
Accepted: September 22, 2009
Published online: February 7, 2010
Abstract

AIM: To investigate the incidence, location, clinical presentation, diagnosis and effectiveness of endoscopic treatment of gastric Dieulafoy’s lesion (DL) in China.

METHODS: All patients who received emergency upper gastrointestinal (GI) endoscopy due to gastric DL from February 2000 to August 2008 at GI endoscopy center of Renmin Hospital of Wuhan University were included in this study. The clinical presentation, medical history, location and characteristics of DL methods and effectiveness of therapy of patients with DL were retrospectively analysed by chart reviews. Long-term follow-up data were collected at outpatient clinics or telephone interviews.

RESULTS: Fifteen patients were diagnosized with DL, which account for 1.04% of the source of bleeding in acute non-variceal upper GI bleeding. Common comorbidities were found in one patient with hypertension and diabetic mellitus. Hemoclip or combined therapy with hemoclip produced primary hemostasis in 92.8% (13/14) of patients.

CONCLUSION: DL is uncommon but life-threatening in China. Hemoclip proved to be safe and effective in controlling bleeding from DL.

Keywords: Gastric Dieulafoy’s lesion; Clinical analysis; Endoscopic analysis