Case Report
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World J Gastroenterol. Sep 7, 2010; 16(33): 4237-4242
Published online Sep 7, 2010. doi: 10.3748/wjg.v16.i33.4237
Multi-site abdominal tuberculosis mimics malignancy on 18F-FDG PET/CT: Report of three cases
Geng Tian, Yong Xiao, Bin Chen, Hong Guan, Qun-Yi Deng
Geng Tian, Department of Tumor, Shenzhen Second People’s Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen 518035, Guangdong Province, China
Yong Xiao, Department of Radiology, Guangdong Frontier Defence Armed Police General Hospital, Shenzhen 518032, Guangdong Province, China
Bin Chen, Department of General Surgery, Shenzhen Second People’s Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen 518035, Guangdong Province, China
Hong Guan, Department of Pathology, Shenzhen Second People’s Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen 518035, Guangdong Province, China
Qun-Yi Deng, Department of Pneumology, Shenzhen Third People’s Hospital, Shenzhen 518020, Guangdong Province, China
Author contributions: Tian G and Xiao Y designed the research; Tian G, Xiao Y and Deng QY performed the research; Chen B and Guan H analyzed the data; Tian G wrote the paper.
Correspondence to: Geng Tian, MD, Department of Tumor, Shenzhen Second People’s Hospital, First Affiliated Hospital of Shenzhen University, 3002 Sungang West Road, Shenzhen 518035, Guangdong Province, China. tiangeng666@yahoo.com.cn
Telephone: +86-755-83366388 Fax: +86-755-83356952
Received: April 22, 2010
Revised: May 31, 2010
Accepted: June 7, 2010
Published online: September 7, 2010
Abstract

18F-fluorodeoxyglucose positron emission/computed tomography (18F-FDG PET/CT) imaging, an established procedure for evaluation of malignancy, shows an increased 18F-FDG uptake in inflammatory conditions. We present three patients with abdominal pain and weight loss. Conventional imaging studies indicated that abdominal neoplasm and 18F-FDG PET/CT for assessment of malignancy showed multiple lesions with intense 18F-FDG uptake in abdomen of the three cases. However, the three patients were finally diagnosed with multi-site abdominal tuberculosis (TB). Of them, two were diagnosed with TB by pathology, one was diagnosed with TB clinically. They recovered after anti-TB therapy. Few reports on accumulation of 18F-FDG in abdominal TB are available in the literature. A high index of suspicion is necessary to achieve an early diagnosis and a better outcome of the disease.

Keywords: Abdominal tuberculosis; Differential diagnosis; 18F-fluorodeoxyglucose; Positron emission tomography/computed tomography; Malignancy