Brief Article
Copyright ©2010 Baishideng. All rights reserved
World J Gastroenterol. Jun 7, 2010; 16(21): 2669-2676
Published online Jun 7, 2010. doi: 10.3748/wjg.v16.i21.2669
Fields of applications, diagnostic yields and findings of OMOM capsule endoscopy in 2400 Chinese patients
Zhuan Liao, Rui Gao, Feng Li, Can Xu, Yi Zhou, Jin-Shan Wang, Zhao-Shen Li
Zhuan Liao, Rui Gao, Feng Li, Can Xu, Zhao-Shen Li, Capsule Endoscopy Study Group, Department of Gastroenterology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China
Yi Zhou, Jin-Shan Wang, Jianshan Science and Technology (Group) Co., Ltd., Chongqing 401120, China
Author contributions: Liao Z and Gao R contributed equally to this work; Liao Z and Li ZS designed the research; Zhou Y and Wang JS provided the data; Liao Z, Gao R and Xu C analyzed the data; Liao Z and Li F wrote the paper.
Supported by (in part) Shanghai Educational Development Foundation, Shanghai Chenguang Project, No. 2007CG49
Correspondence to: Zhao-Shen Li, Professor, Capsule Endoscopy Study Group, Department of Gastroenterology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China. zhaoshenli@hotmail.com
Telephone: +86-21-81873241 Fax: +86-21-55620081
Received: February 14, 2010
Revised: March 5, 2010
Accepted: March 12, 2010
Published online: June 7, 2010
Abstract

AIM: To retrospectively analyze the fields of application, diagnostic yields and findings of OMOM capsule endoscopy in Chinese patients.

METHODS: A database including 2400 Chinese patients who received OMOM capsule endoscopy in 27 endoscopy centers in China was retrieved from the Jianshan Science and Technology Ltd. OMOM capsule endoscopy database. The patient’s age, gender, fields of application, the potentially relevant findings, pyloric transit time (PTT), small bowel transit time (SBTT), and complete small-bowel examination rate (CSER) were recorded and analyzed.

RESULTS: Two thousand four hundred patients aged 9-91 years (mean, 49 years), of whom 1510 were males (62.9%), underwent 2400 OMOM capsule endoscopy procedures. One thousand two hundred and thirty two (51.3%) were referred with obscure gastrointestinal bleeding (OGIB), 642 (26.8%) with abdominal pain, and 223 (9.3%) with chronic diarrhea. The overall diagnostic yield was 47.7% (1144/2400). The diagnostic yield of OMOM capsule endoscopy in OGIB subgroup was much higher than in the non-OGIB subgroup (62.4% vs 32.1%, P < 0.001). The most common findings of the small bowel in Chinese patients with OGIB were arteriovenous malformation (28.1%) and tumors (18.9%). There was no significant difference in the diagnostic yield between the male and female patients with OGIB. However, the diagnostic yield in patients aged more than 60 was higher than in patients aged less than 60 (69.8% vs 58.9%, P < 0.001). The median PTT was 41 min (range: 1-544 min) and the mean SBTT was 247.2 ± 88.9 min. The overall CSER was 86.8%.

CONCLUSION: The OMOM capsule endoscopy is a valuable tool for small bowel evaluation with good overall diagnostic yield and CSER.

Keywords: OMOM capsule endoscopy; Obscure gastrointestinal bleeding; Small bowel