Brief Article
Copyright ©2010 Baishideng. All rights reserved.
World J Gastroenterol. Mar 21, 2010; 16(11): 1402-1408
Published online Mar 21, 2010. doi: 10.3748/wjg.v16.i11.1402
Effects on the pouch of different digestive tract reconstruction modes assessed by radionuclide scintigraphy
Dong-Sheng Li, Hui-Mian Xu, Chun-Qi Han, Ya-Ming Li
Dong-Sheng Li, Hui-Mian Xu, Chun-Qi Han, Ya-Ming Li, Department of Oncology, The First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Author contributions: Li DS and Xu HM designed the research; Li DS and Han CQ performed the research; Li DS and Xu HM performed the result analysis; Li YM provided the guidance during the study and partly contributed the financial support.
Correspondence to: Hui-Mian Xu, Professor, Department of Oncology, The First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning Province, China. xuhuimian@126.com
Telephone: +86-24-23256666-6227 Fax: +86-24-22703576
Received: December 9, 2009
Revised: January 17, 2010
Accepted: January 24, 2010
Published online: March 21, 2010
Abstract

AIM: To determine the effect of three digestive tract reconstruction procedures on pouch function, after radical surgery undertaken because of gastric cancer, as assessed by radionuclide dynamic imaging.

METHODS: As a measure of the reservoir function, with a designed diet containing technetium-99m (99mTc), the emptying time of the gastric substitute was evaluated using a 99mTc-labeled solid test meal. Immediately after the meal, the patient was placed in front of a γ camera in a supine position and the radioactivity was measured over the whole abdomen every minute. A frame image was obtained. The emptying sequences were recorded by the microprocessor and then stored on a computer disk. According to a computer processing system, the half-emptying actual curve and the fitting curve of food containing isotope in the detected region were depicted, and the half-emptying actual curves of the three reconstruction procedures were directly compared.

RESULTS: Of the three reconstruction procedures, the half-emptying time of food containing isotope in the Dual Braun type esophagojejunal anastomosis procedure (51.86 ± 6.43 min) was far closer to normal, significantly better than that of the proximal gastrectomy orthotopic reconstruction (30.07 ± 15.77 min, P = 0.002) and P type esophagojejunal anastomosis (27.88 ± 6.07 min, P = 0.001) methods. The half-emptying actual curve and fitting curves for the Dual Braun type esophagojejunal anastomosis were fairly similar while those of the proximal gastrectomy orthotopic reconstruction and P type esophagojejunal anastomosis were obviously separated, which indicated bad food conservation in the reconstructed pouches.

CONCLUSION: Dual Braun type esophagojejunal anastomosis is the most useful of the three procedures for improving food accommodation in patients with a pouch and can retard evacuation of solid food from the reconstructed pouch.

Keywords: Isotope γ-scintigraphy; T1/2 time; Digestive tract reconstruction; 99mTc-DTPA; Emptying time