Editorial
Copyright ©2009 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Oct 14, 2009; 15(38): 4737-4740
Published online Oct 14, 2009. doi: 10.3748/wjg.15.4737
Etiology of chronic pancreatitis: Has it changed in the last decade?
Raffaele Pezzilli
Raffaele Pezzilli, Department of Digestive Diseases and Internal Medicine, Sant’Orsola-Malpighi Hospital, Via Massarenti 9, 40138 Bologna, Italy
Author contributions: Pezzilli R contributed to this paper.
Correspondence to: Dr. Raffaele Pezzilli, Department of Digestive Diseases and Internal Medicine, Sant’Orsola-Malpighi Hospital, Via Massarenti 9, 40138 Bologna, Italy. raffaele.pezzilli@aosp.bo.it
Telephone: +39-51-6364148 Fax: +39-51-6364148
Received: August 3, 2009
Revised: September 7, 2009
Accepted: September 14, 2009
Published online: October 14, 2009
Abstract

The evidence from recent surveys on chronic pancreatitis carried out around the world shows that alcohol remains the main factor associated with chronic pancreatitis, even if at a frequency lower than that reported previously. It has further confirmed that heavy alcohol consumption and smoking are independent risk factors for chronic pancreatitis. Autoimmune pancreatitis accounts for 2%-4% of all forms of chronic pancreatitis, but this frequency will probably increase over the next few years. The rise in idiopathic chronic pancreatitis, especially in India, represents a black hole in recently published surveys. Despite the progress made so far regarding the possibility of establishing the hereditary forms of chronic pancreatitis and the recognition of autoimmune pancreatitis, it is possible that we are more inaccurate today than in the past in identifying the factors associated with chronic pancreatitis in our patients.

Keywords: Cohort studies; Combined modality therapy; Data collection; Genetics; Pancreatitis; Alcoholic; Population