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©2009 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Jul 21, 2009; 15(27): 3431-3433
Published online Jul 21, 2009. doi: 10.3748/wjg.15.3431
Published online Jul 21, 2009. doi: 10.3748/wjg.15.3431
Combined goblet cell carcinoid and mucinous cystadenoma of the vermiform appendix
Khaled O Alsaad, Stefano Serra, Runjan Chetty, Department of Laboratory Medicine and Pathobiology, University of Toronto and University Health Network, 20 Elizabeth Street, 11th Floor, Eaton Wing, Toronto, Ontario M5G 2C4, Canada
Khaled O Alsaad, Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City and College of Medicine, King Saud bin Abdulaziz University for Health Sciences, PO Box 22490, Riyadh 11426 MC 1122, Saudi Arabia
Author contributions: Alsaad KO, Serra S and Chetty R contributed equally to this work. Alsaad KO wrote this manuscript; Serra S and Chetty R contributed to the writing, direction and content and also revised the manuscript.
Correspondence to: Dr. Runjan Chetty, Department of Laboratory Medicine and Pathobiology, University Health Network, Toronto General Hospital, 200 Elizabeth Street, 11th Floor, Eaton Wing, Toronto, Ontario M5G 2C4, Canada. runjan.chetty@uhn.on.ca
Telephone: +1-416-3403661
Fax: +1-416-3405517
Received: September 16, 2008
Revised: June 14, 2009
Accepted: June 21, 2009
Published online: July 21, 2009
Revised: June 14, 2009
Accepted: June 21, 2009
Published online: July 21, 2009
Abstract
Goblet cell carcinoid is an uncommon primary tumor of the vermiform appendix, characterized by dual endocrine and glandular differentiation. Whether goblet cell carcinoid represents a morphological variant of appendiceal classical carcinoid or a mucin-producing adenocarcinoma is a matter of conjecture. Rare cases of goblet cell carcinoid with other concomitant appendiceal epithelial neoplasms have been documented. In this report, we describe a rare case of combined appendiceal goblet cell carcinoid and mucinous cystadenoma, and discuss the possible histopathogenesis of this combination.