Brief Articles
Copyright ©2009 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Jul 21, 2009; 15(27): 3417-3420
Published online Jul 21, 2009. doi: 10.3748/wjg.15.3417
Hepatic angiomyolipoma: Dynamic computed tomography features and clinical correlation
Bin Yang, Wen-Hui Chen, Qiao-Yun Li, Jing-Jing Xiang, Ru-Jun Xu
Bin Yang, Wen-Hui Chen, Department of Radiology, Hangzhou First People’s Hospital, Hangzhou 310006, Zhejiang Province, China
Qiao-Yun Li, Jing-Jing Xiang, Ru-Jun Xu, Department of Pathology, Hangzhou First People’s Hospital, Hangzhou 310006, Zhejiang Province, China
Author contributions: Yang B designed the research; Yang B, Chen WH, Li QY, Xiang JJ and Xu RJ performed the research; Yang B wrote the paper.
Correspondence to: Dr. Bin Yang, Department of Radiology, Hangzhou First People’s Hospital, Hangzhou 310006, Zhejiang Province, China. yb1974126@sina.com
Telephone: +86-571-87065701-10256
Fax: +86-571-87915031
Received: April 4, 2009
Revised: June 2, 2009
Accepted: June 9, 2009
Published online: July 21, 2009
Abstract

AIM: To study the dynamic computed tomography (CT) features of hepatic angiomyolipoma (AML) in patients with or without tuberous sclerosis complex (TSC).

METHODS: The clinical information, CT findings and histopathological results of hepatic AML were analyzed retrospectively in 10 patients.

RESULTS: Hepatic AML was prone to occur in female patients (7/10), and most of the patients (8/10) had no specific symptoms. All tumors presented as well-defined, unenveloped nodules in the liver. Six patients with sporadic hepatic AML had a solitary hepatic nodule with a definite fat component. Non-fat components of the hepatic lesions were enhanced earlier and persistently. Prominent central vessels were noted in the portal venous phase in three patients. In four patients with hepatic AML and TSC, most of the nodules were within the peripheral liver. Seven fat-deficient nodules were found with earlier contrast enhancement and rapid contrast material washout in two patients. Lymphangioleiomyomatosis was found in one patient.

CONCLUSION: Imaging features of hepatic AML are characteristic. Correct diagnosis preoperatively can be made in combination with clinical features.

Keywords: Lymphangioleiomyomatosis, X-ray, Computed tomography, Angiomyolipoma, Tuberous sclerosis complex