Case Report
Copyright ©2009 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Jun 7, 2009; 15(21): 2665-2668
Published online Jun 7, 2009. doi: 10.3748/wjg.15.2665
Bone and brain metastases from ampullary adenocarcinoma
Ioannis A Voutsadakis, Stergios Doumas, Konstantinos Tsapakidis, Maria Papagianni, Christos N Papandreou
Ioannis A Voutsadakis, Stergios Doumas, Konstantinos Tsapakidis, Maria Papagianni, Christos N Papandreou, Division of Medical Oncology, University Hospital of Larissa, Larissa 41110, Greece
Author contributions: Voutsadakis IA conceptualized and wrote the paper, provided clinical care and performed the research; Doumas S performed research and co-authored the paper; Tsapakidis K and Papagianni M performed research and collected data; Papandreou CN revised the paper.
Correspondence to: Ioannis A Voutsadakis, Division of Medical Oncology, University Hospital of Larissa, Larissa 41110, Greece. ivoutsadakis@yahoo.com
Telephone: +30-2410-682028
Fax: +30-2410-682027
Received: February 25, 2009
Revised: May 5, 2009
Accepted: May 12, 2009
Published online: June 7, 2009
Abstract

Ampullary carcinoma is the second most common cancer of the peri-ampullary area after pancreatic carcinoma and metastasizes mostly intra-abdominally and to the liver. Extra-abdominal metastases are less frequent. In this report we describe the case of a patient with resected adenocarcinoma of the ampulla of Vater who developed skeletal metastases in the lower extremity and brain metastases. We briefly discuss aspects of this comparatively rare gastrointestinal malignancy.

Keywords: Adenocarcinoma, Ampulla of Vater, Peri-ampullary, Metastases, Prognosis