Filipovic N, Cvetkovic A, Isailovic V, Matovic Z, Rosic M, Kojic M. Computer simulation of flow and mixing at the duodenal stump after gastric resection. World J Gastroenterol 2009; 15(16): 1990-1998 [PMID: 19399932 DOI: 10.3748/wjg.15.1990]
Corresponding Author of This Article
Nenad Filipovic, Faculty of Mechanical Engineering, University of Kragujevac, S Janjica 6, Kragujevac 34000, Serbia. fica@kg.ac.rs
Article-Type of This Article
Brief Articles
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Nenad Filipovic, Aleksandar Cvetkovic, Velibor Isailovic, Zoran Matovic, Mirko Rosic, Faculty of Mechanical Engi-neering, University of Kragujevac, Kragujevac 34000, Serbia
Nenad Filipovic, Velibor Isailovic, Milos Kojic, Research and Development Center for Bioengineering, Kragujevac 34000, Serbia
Nenad Filipovic, Milos Kojic, Harvard School of Public Health, Boston, MA 02115, United States
Aleksandar Cvetkovic, Zoran Matovic, Clinical Center Kragujevac, Kragujevac 34000, Serbia
Mirko Rosic, Medical Faculty Kragujevac, Kragujevac 34000, Serbia
Milos Kojic, The University of Texas Health Science Center, Houston TX77030, United States
Author contributions: Filipovic N, Kojic M and Rosic M designed research; Cvetkovic A, Matovic Z and Rosic M designed and performed experimental research; Filipovic N and Isailovic V created and ran computer simulations; Filipovic N, Kojic M and Cvetkovic A wrote the paper.
Correspondence to: Nenad Filipovic, Faculty of Mechanical Engineering, University of Kragujevac, S Janjica 6, Kragujevac 34000, Serbia. fica@kg.ac.rs
Telephone: +381-34-334379
Fax: +381-34-333192
Received: December 23, 2008 Revised: March 5, 2009 Accepted: March 12, 2009 Published online: April 28, 2009
Abstract
AIM: To investigate the flow and mixing at the duodenal stump after gastric resection, a computer simulation was implemented.
METHODS: Using the finite element method, two different Billroth II procedure cases (A and B) were modeled. Case A was defined with a shorter and almost straight duodenal section, while case B has a much longer and curved duodenal section. Velocity, pressure and food concentration distribution were determined and the numerical results were compared with experimental observations.
RESULTS: The pressure distribution obtained by numerical simulation was in the range of the recorded experimental results. Case A had a more favorable pressure distribution in comparison with case B. However, case B had better performance in terms of food transport because of more continual food distribution, as well as better emptying of the duodenal section.
CONCLUSION: This study offers insight into the transport process within the duodenal stump section after surgical intervention, which can be useful for future patient-specific predictions of a surgical outcome.
