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©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Feb 21, 2008; 14(7): 991-993
Published online Feb 21, 2008. doi: 10.3748/wjg.14.991
Published online Feb 21, 2008. doi: 10.3748/wjg.14.991
Venous thromboembolism with inflammatory bowel disease
Hugh James Freeman, Department of Medicine (Gastroen-terology), University of British Columbia, Vancouver, BC, Canada
Author contribution: Freeman HJ contributed all to this paper.
Correspondence to: Dr. Hugh James Freeman, MD, FRCPC, FACP, Department of Medicine (Gastroenterology), University of British Columbia Hospital, 2211 Wesbrook Mall, Vancouver, BC V6T 1W5, Canada. hugfree@shaw.ca
Telephone: +1-604-8227216
Fax: +1-604-8227236
Received: December 4, 2007
Revised: January 3, 2008
Published online: February 21, 2008
Revised: January 3, 2008
Published online: February 21, 2008
Abstract
Venous thrombosis and thromboembolism appear to be increased in patients with inflammatory bowel disease. Although several acquired and genetic risk factors are known, about half that develop a thromboembolic event have no identifiable risk factor. Control of the inflammatory process is thought to be the key factor in risk reduction for thrombotic events. Prophylactic use of anticoagulants is not universally recommended, but possible use should be reviewed in an individual patient after evaluation of the risks, such as hemorrhage, compared to potential benefits. Particular consideration should be given if there has been a prior thrombotic event, if hospitalization will require surgery, or if an underlying coagulation disorder is present.
Keywords: Venous thrombosis; Thromboembolism; Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis