Case Report
Copyright ©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Nov 28, 2008; 14(44): 6884-6887
Published online Nov 28, 2008. doi: 10.3748/wjg.14.6884
Gastric carcinoid tumor in a patient with a past history of gastrointestinal stromal tumor of the stomach
Chien-Yuan Hung, Ming-Jen Chen, Shou-Chuan Shih, Tsang-Pai Liu, Yu-Jan Chan, Tsang-En Wang, Wen-Hsiung Chang
Chien-Yuan Hung, Ming-Jen Chen, Shou-Chuan Shih, Tsang-En Wang, Wen-Hsiung Chang, Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital and Mackay Medicine, Nursing and Management College, Taipei, Taiwan, China
Tsang-Pai Liu, Department of General Surgery, Mackay Memorial Hospital, Taipei, Taiwan, China
Yu-Jan Chan, Department of Pathology, Mackay Memorial Hospital, Taipei, Taiwan, China
Author contributions: Liu TP and Wang TE conducted literature review; Hung CY and Chen MJ wrote this article; Chan YJ reviewed the gastric specimen and performed special staining; Chang WH supported this work by critical reading of the manuscript and Shih SC supervised the final editing.
Correspondence to: Dr. Ming-Jen Chen, Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, No. 92, Sec. 2, Chungshan North Road, Taipei, Taiwan, China. mingjen.ch@msa.hinet.net
Telephone: +886-2-25433535-2260 Fax: +886-2-25433642
Received: May 29, 2008
Revised: November 7, 2008
Accepted: November 14, 2008
Published online: November 28, 2008
Abstract

Gastrointestinal stromal tumor is the most common mesenchymal tumor in the gastrointestinal tract. It may coexist with other type of cancers, and if so, the tumors usually involve the stomach. The most common associated cancers are gastrointestinal carcinomas. We report a 65-year-old woman with a history of gastric gastrointestinal stromal tumor who had undergone subtotal segmental gastrectomy. New polypoid lesions were detected on a follow-up gastroscopy one year later. The lesions were biopsied and found to be carcinoid tumors. There was serum hypergastrinemia, and type 1 gastric carcinoid tumor was diagnosed. A total gastrectomy was performed. Pathologic examination revealed both carcinoid tumors and a recurrent gastrointestinal stromal tumor.

Keywords: Hypergastrinemia; Multiple primary neoplasms; Stomach; Gastrointestinal stromal tumor; Carcinoid tumor