Reddy VB, Aslanian H, Suh N, Longo WE. Asymptomatic ileal adenocarcinoma in the setting of undiagnosed Crohn’s disease. World J Gastroenterol 2008; 14(29): 4690-4693 [PMID: 18698685 DOI: 10.3748/wjg.14.4690]
Corresponding Author of This Article
Dr. Walter E Longo, Department of Surgery, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut 06510, United States. walter.longo@yale.edu
Article-Type of This Article
Case Report
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World J Gastroenterol. Aug 7, 2008; 14(29): 4690-4693 Published online Aug 7, 2008. doi: 10.3748/wjg.14.4690
Asymptomatic ileal adenocarcinoma in the setting of undiagnosed Crohn’s disease
Vikram B Reddy, Harold Aslanian, Namsoo Suh, Walter E Longo
Vikram B Reddy, Walter E Longo, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06510, United States
Harold Aslanian, Department of Gastroenterology, Yale University School of Medicine, New Haven, Connecticut 06510, United States
Namsoo Suh, Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06510, United States
Author contributions: Reddy VB and Longo WE contributed equally to this work; Aslanian H performed the colonoscopy and computed tomography imaging; Suh N performed the pathologic examination; Reddy VB and Longo WE wrote the paper.
Correspondence to: Dr. Walter E Longo, Department of Surgery, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut 06510, United States. walter.longo@yale.edu
Telephone: +1-203-7852616
Fax: +1-203-7852615
Received: October 20, 2007 Revised: July 4, 2008 Accepted: July 11, 2008 Published online: August 7, 2008
Abstract
A 53-year old previously healthy male underwent a screening colonoscopy for detection of a potential colorectal neoplasm. The terminal ileum was intubated and a mass was noted. Examination of the colon was normal. The biopsy of the ileal mass was consistent with an adenocarcinoma arising from the terminal ileum. His father who had never been previously ill from gastrointestinal disease died of natural causes, but was found to have Crohn’s disease postmortem. The patient underwent exploratory laparotomy and a right hemicolectomy with a 30 cm section of terminal ileum in continuity. Findings were consistent with ileal adenocarcinoma in the setting of Crohn’s disease. The patient made an uneventful recovery. The pathology was stage 1 adenocarcinoma. This is a unique case in that on a screening colonoscopy, a favorable ileal adenocarcinoma was discovered in the setting of asymptomatic, undiagnosed ileal Crohn’s disease in a patient whose father had Crohn’s disease diagnosed postmortem.
