Zepeda-Gómez S, Camacho J, Oviedo-Cárdenas E, Lome-Maldonado C. Gastric infiltration of diffuse large B-cell lymphoma: Endoscopic diagnosis and improvement of lesions after chemotherapy. World J Gastroenterol 2008; 14(27): 4407-4409 [PMID: 18666335 DOI: 10.3748/wjg.14.4407]
Corresponding Author of This Article
Sergio Zepeda-Gómez, Department of Gastrointestinal Endoscopy, Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”, Vasco de Quiroga 15, Tlalpan 14000, Mexico City, Mexico. sergiozepeda@medscape.com
Article-Type of This Article
Case Report
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World J Gastroenterol. Jul 21, 2008; 14(27): 4407-4409 Published online Jul 21, 2008. doi: 10.3748/wjg.14.4407
Gastric infiltration of diffuse large B-cell lymphoma: Endoscopic diagnosis and improvement of lesions after chemotherapy
Sergio Zepeda-Gómez, Jesús Camacho, Edgar Oviedo-Cárdenas, Carmen Lome-Maldonado
Sergio Zepeda-Gómez, Jesús Camacho, Department of Gastrointestinal Endoscopy, Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”, Tlalpan 14000, Mexico City, Mexico
Edgar Oviedo-Cárdenas, Carmen Lome-Maldonado, Department of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”, Tlalpan 14000, Mexico City, Mexico
Author contributions: Zepeda-Gómez S and Camacho J contributed to the endoscopic evaluation and follow-up, literature research and writing of the case report; Zepeda-Gómez S discussed the case; Oviedo-Cárdenas E and Lome-Maldonado C contributed to the histopathological analysis and literature review.
Correspondence to: Sergio Zepeda-Gómez, Department of Gastrointestinal Endoscopy, Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”, Vasco de Quiroga 15, Tlalpan 14000, Mexico City, Mexico. sergiozepeda@medscape.com
Telephone: +52-5-54870900
Fax: +52-5-556522391
Received: February 14, 2008 Revised: June 19, 2008 Accepted: June 26, 2008 Published online: July 21, 2008
Abstract
Diffuse large B-cell lymphoma (DLBCL) is the most common histologic subtype of the non-Hodgkin’s lymphoma (NHL) accounting for about 40% of all NHLs. This is a case report about the endoscopic appearance of a DLBCL with infiltration to the stomach in a 39-year-old female. She had a 6-mo history of lumbar and left upper quadrant pain with intermittent episodes of melena. A computer tomography (CT) scan showed mural thickening of the gastric antrum. Endoscopic examination revealed multiple gastric ulcers. Definite diagnosis could be made by endoscopic biopsies and the patient had a good response to chemotherapy. This response correlated well with a further endoscopic follow-up. A follow-up endoscopic examination could be considered to evaluate a good response to chemotherapy in DLBCL patients with secondary gastric dissemination.
