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World J Gastroenterol. May 28, 2008; 14(20): 3212-3217
Published online May 28, 2008. doi: 10.3748/wjg.14.3212
Incidence of reflux esophagitis and Helicobacter pylori infection in diabetic patients
Ken Ariizumi, Tomoyuki Koike, Shuichi Ohara, Yoshifumi Inomata, Yasuhiko Abe, Katsunori Iijima, Akira Imatani, Yoshitomo Oka, Tooru Shimosegawa
Ken Ariizumi, Tomoyuki Koike, Shuichi Ohara, Yoshifumi Inomata, Yasuhiko Abe, Katsunori Iijima, Akira Imatani, Tooru Shimosegawa, Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 9808574, Japan
Yoshitomo Oka, Division of Diabetes and Metabolic Diseases, Tohoku University Graduate School of Medicine, Sendai, Miyagi 9808574, Japan
Author contributions: Ariizumi K, Koike T, Ohara S, Oka Y designed the research; Ariizumi K, Koike T, Ohara S, Inomata Y, Abe Y, Iijima K, Imatani A, Oka Y, Shimosegawa T performed the research; Ariizumi K, Koike T, Ohara S wrote the paper.
Correspondence to: Ken Ariizumi, Division of Gastro-enterology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 9808574, Japan. kariizumi@int3.med.tohoku.ac.jp
Telephone: +81-22-7177171
Fax: +81-22-7177177
Received: January 9, 2008
Revised: March 30, 2008
Accepted: April 6, 2008
Published online: May 28, 2008
Abstract

AIM: To investigate the incidence of reflux esophagitis (RE) and H pylori infection in the diabetic patient.

METHODS: The incidence of RE and H pylori infection were investigated in 85 patients with diabetes mellitus and the results were compared with controls.

RESULTS: The incidence of RE in diabetic patients was 17.6%. Although this tended to be higher in diabetic patients, there were no statistically significant differences between diabetic patients and controls. The incidence of H pylori infection in diabetic patients was 53.7% but no statistically significant difference was seen between diabetic patients and controls in the incidence of H pylori infection.

CONCLUSION: No significant differences could be seen between diabetic patients and controls in the incidence of RE and H pylori infection.

Keywords: Diabetes mellitus; Reflux esophagitis; Helicobacter pylori