Case Report
Copyright ©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Apr 7, 2008; 14(13): 2121-2123
Published online Apr 7, 2008. doi: 10.3748/wjg.14.2121
Diagnosis and treatment of Gardner syndrome with gastric polyposis: A case report and review of the literature
Guo-Li Gu, Shi-Lin Wang, Xue-Ming Wei, Li Bai
Guo-Li Gu, Shi-Lin Wang, Xue-Ming Wei, Department of General Surgery, the General Hospital of Chinese PLA Air Force, Beijing 100036, China
Li Bai, Department of Digestive Disease, the General Hospital of Chinese PLA Air Force, Beijing 100036, China
Author contributions: Wang SL and Gu GL designed the study; Gu GL collected the clinical data and wrote the manuscript; Wang SL, Wei XM and Bai L revised the manuscript.
Correspondence to: Shi-Lin Wang, Department of General Surgery, the General Hospital of Chinese PLA Air Force, Beijing 100036, China. kzggl@163.com
Telephone: +86-10-66928302
Fax: +86-10-66928302
Received: January 8, 2008
Revised: February 26, 2008
Published online: April 7, 2008
Abstract

Gardner syndrome (GS) is an autosomal dominant disease characterized by the presence of colonic polyposis, osteoma and soft tissue tumors. It is regarded as a clinical subgroup of familial adenomatous polyposis (FAP) and may present at any age from 2 mo to 70 years with a variety of symptoms, either colonic or extracolonic. We present a case of a 23-year-old female patient with GS who presented with gastric polyposis and was successively treated with restorative proctocolectomy in combination with ileal pouch anal anastomosis (RPC/IPAA), ileostomy, ileostomy closure operation, snare polypectomy during 8 mo. After operation, the patient took oral traditional Chinese medicine pills made of Fructus mume and Bombyx batryticatu for about 6 mo. The innutrition and anaemia of this patient were gradually improved. Gastroscopy showed that the remnant gastric polypi gradually decreased and finally disappeared 19 mo after the first operation. The patient had 2-3 times of solid stool per day at the time we wrote this paper.

Keywords: Gardner syndrome, Familial adenomatous polyposis, Colectomy, Ileal pouch anal anastomosis, Stomach polyposis, Hereditary nonpolyposis colorectal cancer