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©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Apr 7, 2008; 14(13): 1984-1989
Published online Apr 7, 2008. doi: 10.3748/wjg.14.1984
Published online Apr 7, 2008. doi: 10.3748/wjg.14.1984
Endoscopic mucosal resection in the upper gastrointestinal tract
Anis Ahmadi, Peter Draganov, Division Gastroenterology Hepatology and Nutrition, University of Florida, Gainesville, Florida 32610, United States
Author contributions: Ahmadi A and Draganov P contributed equally to this work.
Correspondence to: Peter Draganov, Dr, Division Gastroenterology Hepatology and Nutrition, University of Florida, Gainesville, 1600 SW Archer Road PO Box 100214, Florida 32610, United States. dragapv@medicine.ufl.edu
Telephone: +1-352-3922877
Fax: +1-352-3923618
Received: December 15, 2007
Revised: January 31, 2008
Published online: April 7, 2008
Revised: January 31, 2008
Published online: April 7, 2008
Abstract
Endoscopic mucosal resection (EMR) is a technique used to locally excise lesions confined to the mucosa. Its main role is the treatment of advanced dysplasia and early gastrointestinal cancers. EMR was originally described as a therapy for early gastric cancer. Recently its use has expanded as a therapeutic option for ampullary masses, colorectal cancer, and large colorectal polyps. In the Western world, the predominant indication for EMR in the upper gastrointestinal tract is the staging and treatment of advance dysplasia and early neoplasia in Barrett’s esophagus. This review will describe the basis, indications, techniques, and complications of EMR, and its role in the management of Barrett’s esophagus.
Keywords: Endoscopic mucosal resection; Mucosal resection; Barrett’s esophagus; Barrett’s dysplasia; Therapeutic endoscopy