Case Report
Copyright ©2007 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Jul 21, 2007; 13(27): 3758-3759
Published online Jul 21, 2007. doi: 10.3748/wjg.v13.i27.3758
Diagnostic approach using endosonography guided fine needle aspiration for lymphadenopathy in primary sclerosing cholangitis
Shintaro Tsukinaga, Hiroo Imazu, Yujiro Uchiyama, Hiroshi Kakutani, Akira Kuramoti, Masayuki Kato, Keisuke Kanazawa, Tsuyoshi Kobayashi, Yasuyuki Searashi, Hisao Tajiri
Shintaro Tsukinaga, Hiroo Imazu, Yujiro Uchiyama, Hiroshi Kakutani, Akira Kuramoti, Masayuki Kato, Keisuke Kanazawa, Department of Endoscopy, Jikei University School of Medicine, Tokyo, Japan
Tsuyoshi Kobayashi, Yasuyuki Searashi, Hisao Tajiri, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Jikei University School of Medcine, Japan
Author contributions: All authors contributed equally to the work.
Correspondence to: Hiroo Imazu, MD, Department of Endoscopy, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minatoku, Tokyo 105-8461, Japan. himazu21@aol.com
Telephone: +81-3-34331111-3181 Fax: +81-3-3459452
Received: March 18, 2007
Revised: April 10, 2007
Accepted: April 16, 2007
Published online: July 21, 2007
Abstract

We report a case of primary sclerosing cholangitis (PSC) with benign lyphadenopathy which was diagnosed with endosonography guided fine needle aspiration (EUS-FNA). A 65-year-old woman was admitted to Jikei University Hospital with severe jaundice. Although endoscopic retrograde cholangiography and liver biopsy revealed the findings consistent with PSC, abdominal computed tomography revealed numerous large perihepatic lymph nodes with a maximum diameter of more than 3 cm. Therefore, EUS-FNA was done in order to exclude malignant lymphadenopathy, and adequate specimens obtained by EUS-FNA showed reactive hyperplasia of lymphnode. The patients were scheduled to undergo liver transplantation.

Keywords: Endosonography guided fine needle aspiration, Primary sclerosing cholangitis, Lymphadenopathy