Tc-99m ciprofloxacin imaging in acute cholecystitis

doi:10.3748/wjg.v13.i23.3249

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Jun 21, 2007 (publication date) through Nov 8, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 21, 2007; 13(23): 3249-3252
Published online Jun 21, 2007. doi: 10.3748/wjg.v13.i23.3249

Tc-99m ciprofloxacin imaging in acute cholecystitis

Yun-Mee Choe, Wonsick Choe, Keon-Young Lee, Seung-Ik Ahn, Kwang Kim, Young Up Cho, Sun Keun Choi, Yoon-Seok Hur, Sei-Joong Kim, Kee-Chun Hong, Seok-Hwan Shin, Kyung-Rae Kim, Ze-Hong Woo

Yun-Mee Choe, Keon-Young Lee, Seung-Ik Ahn, Kwang Kim, Young Up Cho, Sun Keun Choi, Yoon-Seok Hur, Sei-Joong Kim, Kee-Chun Hong, Seok-Hwan Shin, Kyung-Rae Kim, Ze-Hong Woo, Department of Surgery, Inha University Hospital, Incheon, South Korea

Wonsick Choe, Department of Nuclear Medicine, Gachon Medical School, Incheon, South Korea

Author contributions: All authors contributed equally to the work.

Supported by Inha University Research Funds of 2004

Correspondence to: Seung-Ik Ahn, MD, Department of Surgery, Inha University Hospital, 7-206, 3 Ga Shinheung-dong, Jung-Gu, Incheon 400-711, South Korea. siahn@inha.ac.kr

Telephone: +82-32-8902250 Fax: +82-32-8903097

Received: January 26, 2007
Revised: April 2, 2007
Accepted: April 23, 2007
Published online: June 21, 2007

Abstract

AIM: To evaluate the efficacy of a new nuclear imaging Infecton (Tc-99m ciprofloxacin) for the diagnosis of acute cholecystitis.

METHODS: Sixteen patients thought to have acute cholecystitis were included in this study. The diagnosis of acute cholecystitis was made based on clinical symptoms and ultrasonographic and pathologic findings.

RESULTS: The 16 patients were composed of 12 acute and 4 chronic cholecystitis patients. Twelve patients with acute cholecystitis were image-positive, including one false-positive. Four patients with chronic cholecystitis were image-negative, of whom three were true-negative. This nuclear imaging had a sensitivity of 91.7%, a specificity of 75%, a positive-predictive value of 91.7%, and a negative-predictive value of 75%.

CONCLUSION: Tc-99m ciprofloxacin imaging is easy to perform and applicable for the diagnosis of acute cholecystitis.

Keywords: Acute cholecystitis; Diagnosis; Tc-99m ciprofloxacin nuclear imaging