Gallbladder villous adenoma in a patient with acromegaly: A case report

doi:10.3748/wjg.v13.i22.3144

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Jun 14, 2007 (publication date) through Nov 30, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

World J Gastroenterol. Jun 14, 2007; 13(22): 3144-3146
Published online Jun 14, 2007. doi: 10.3748/wjg.v13.i22.3144

Gallbladder villous adenoma in a patient with acromegaly: A case report

Miodrag Krstic, Tamara Alempijevic, Bojan Stimec, Marjan Micev, Miroslav Milicevic, Dragan Micic, Goran Jankovic

Miodrag Krstic, Tamara Alempijevic, Goran Jankovic, Clinic for Gastroenterology, Clinical Center of Serbia, Belgrade, Serbia

Bojan Stimec, Institute for Anatomy, School of Medicine, University of Belgrade, Serbia

Marjan Micev, Department of Pathohistology, Clinical Center of Serbia, Belgrade, Serbia

Miroslav Milicevic, Clinic for Digestive Surgery, Clinical Center of Serbia, Belgrade, Serbia

Dragan Micic, Institute of Endocrinology, Diabetes and Diseases of Metabolism, Clinical Center of Serbia, Belgrade, Serbia

Author contributions: All authors contributed equally to the work.

Correspondence to: Miodrag Krstic, Clinical Center of Serbia, Clinic for Gastroenterology, 2 Koste Todorovica, Belgrade 11000, Serbia. misa@tehnicom.net

Telephone: +381-11-3615575 Fax: +381-11-3615575

Received: February 13, 2007
Revised: March 3, 2007
Accepted: March 15, 2007
Published online: June 14, 2007

Abstract

Villous adenomas are benign epithelial lesions with malignant potential that can occur in any part of the gastrointestinal tract. We present a case of a middle age woman with acromegaly who was investigated for nonspecific gastrointestinal complaints. Ultrasonography and subsequent endosonography diagnosed a large (4.5 cm), hyperechoic, sessile polyp with numerous pedicles. An open cholecystectomy was performed and revealed a villous adenoma with several foci of carcinoma in situ. Detailed investigations showed no other tumors of the gastrointestinal tract. After five years of follow-up, the patient reports no complaints, and the results of laboratory testing and imaging studies are within the normal range.

Keywords: Villous adenoma; Gallbladder; Acromegaly; Endosonography