Case Report
Copyright ©2007 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Jun 14, 2007; 13(22): 3141-3143
Published online Jun 14, 2007. doi: 10.3748/wjg.v13.i22.3141
Distant skeletal muscle metastasis from intrahepatic cholangiocarcinoma presenting as Budd-Chiari syndrome
Oh Sung Kwon, Dae Won Jun, Sang Heum Kim, Mee Yeon Chung, Nam In Kim, Moon Hee Song, Han Hyo Lee, Seung Hwan Kim, Yoon Ju Jo, Young Sook Park, Jong Eun Joo
Oh Sung Kwon, Dae Won Jun, Mee Yeon Chung, Nam In Kim, Moon Hee Song, Han Hyo Lee, Seung Hwan Kim, Yoon Ju Jo, Young Sook Park, Department of Internal Medicine, Eulji University Hospital, Seoul, Korea
Sang Heum Kim, Department of Radiology, Eulji University Hospital, Seoul, Korea
Jong Eun Joo, Department of Pathology, Eulji University Hospital, Seoul, Korea
Author contributions: All authors contributed equally to the work.
Correspondence to: Dae Won Jun, Eulji University Hospital, 280-1 Hagye 1 dong, Nowon gu, Eulji Hospital, Internal medicine, Seoul 139-711, Korea. noshin1004@yahoo.co.kr
Telephone: +82-2-9708494 Fax: +82-2-9708621
Received: February 10, 2007
Revised: March 3, 2007
Accepted: March 15, 2007
Published online: June 14, 2007
Abstract

Intrahepatic cholangiocarcinoma is a malignant neoplasm arising from the biliary epithelium, which frequently invades adjacent organs or metastasizes to other visceral organs such as the lungs, bones, adrenals, and brain. However, distant skeletal muscle metastasis of cholangiocarcinoma has never been described before to the best of our knowledge and, furthermore, Budd-Chiari syndrome secondary to intrahepatic cholangiocarcinoma is also extremely rare. Here we present the first case overall of distant muscle metastasis from intrahepatic cholangiocarcinoma presenting as Budd-Chiari syndrome. A 44-year-old man admitted to the hospital with complaints of abdominal distension, edema of both legs, back pain and anorexia of 30 d' duration. Computed tomography and ultrasonography-guided percutaneous muscle biopsy established intrahepatic cholangiocarcinoma with disseminated thrombosis from inferior vena cava to bilateral iliac and femoral veins, and multiple skeletal muscle metastases in bilateral buttock and erector spinal muscle.

Keywords: Intrahepatic Cholangiocarcinoma; Metastasis; Skeletal muscle; Budd-Chiari syndrome