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©2006 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Feb 28, 2006; 12(8): 1317-1320
Published online Feb 28, 2006. doi: 10.3748/wjg.v12.i8.1317
Published online Feb 28, 2006. doi: 10.3748/wjg.v12.i8.1317
Small bowel adenocarcinoma in Crohn’s disease: A case report and review of literature
Irmgard E Kronberger, Ivo W Graziadei, Wolfgang Vogel, Department of Gastroenterology and Hepatology, Medical University Innsbruck, Austria
Author contributions: All authors contributed equally to the work.
Correspondence to: Irmgard E Kronberger, c/o Wolfgang Vogel, MD, Department of Gastroenterology and Hepatology, Anichstrasse 35, A-6020 Innsbruck, Austria. ie.kronberger@aon.at
Telephone: +43-512-50423401 Fax: +43-512-50424052
Received: June 22, 2005
Revised: July 15, 2005
Accepted: July 28, 2005
Published online: February 28, 2006
Revised: July 15, 2005
Accepted: July 28, 2005
Published online: February 28, 2006
Abstract
Small bowel adenocarcinomas are remarkable for their rarity, difficult diagnosis and poor prognosis. Here we report an unusual case of a 33-year-old patient in whom infiltrative adenocarcinoma of the small bowel was diagnosed after a 10-year history of Crohn’s disease. In most previously reported cases, detection of Crohn’s disease was subsequent to that of carcinoma of the small bowel or the patients involved had an even longer history of the disease. Our literature review suggests that the risk of small bowel adenocarcinoma is higher in patients with Crohn’s disease than in the overall population. We present details on epidemiology as well as clinical and diagnostic aspects of this rare disease entity.
Keywords: Crohn’s disease; Small bowel adenocarcinoma; Case report