Case Report
Copyright ©2006 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Jul 14, 2006; 12(26): 4250-4252
Published online Jul 14, 2006. doi: 10.3748/wjg.v12.i26.4250
Multiple von Meyenburg complexes mimicking diffuse liver metastases from esophageal squamous cell carcinoma
Stefan Fritz, Thilo Hackert, Hendrik Blaker, Werner Hartwig, Lutz Schneider, Markus W Buchler, Jens Werner
Stefan Fritz, Thilo Hackert, Werner Hartwig, Lutz Schneider, Markus W Buchler, Jens Werner, Departments of General and Visceral Surgery, University of Heidelberg, Germany
Hendrik Blaker, Departments of Pathology, University of Heidelberg, Germany
Author contributions: All authors contributed equally to the work.
Correspondence to: Jens Werner, MD, Departments of General and Visceral Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany. jens.werner@med.uni-heidelberg.de
Telephone: +49-6221-566920 Fax: +49-6221-564863
Received: February 6, 2006
Revised: February 21, 2006
Accepted: February 28, 2006
Published online: July 14, 2006
Abstract

Von Meyenburg complexes are benign liver lesions consisting of adenomatous bile duct proliferates. We present two patients suffering from esophageal cancer accompanied by the occurrence of von Meyenburg complexes. Preoperative computerized tomography (CT) of the liver had not shown these lesions. In one of the patients, diffuse nodular manifestation was found in both liver lobes, mimicking diffuse hepatic metastases. Intraoperative frozen section revealed the benign nature of the lesions in both cases. The patients underwent esophageal resection without complications. To the best of our knowledge, the coincidence of von Meyenburg complexes and esophageal cancer has never been reported before. This uncommon entity should be taken into consideration as a differential diagnosis of liver lesions in malignancies. It underlines the importance of intraoperative frozen section for liver lesions of unknown origin.

Keywords: Von Meyenburg complexes; Bile duct hamartomas; Esophageal carcinoma; Liver metastasis