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World J Gastroenterol. Jul 7, 2006; 12(25): 4101-4103
Published online Jul 7, 2006. doi: 10.3748/wjg.v12.i25.4101
Published online Jul 7, 2006. doi: 10.3748/wjg.v12.i25.4101
Successful treatment for esophageal carcinoma with lung metastasis by induction chemotherapy followed by salvage esophagectomy: Report of a case
Shin Ichi Kosugi, Tatsuo Kanda, Satoru Nakagawa, Kazuhito Yajima, Manabu Ohashi, Katsuyoshi Hatakeyama, Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata City, Japan
Tadashi Nishimaki, First department of Surgery, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan
Author contributions: All authors contributed equally to the work.
Correspondence to: Shin Ichi Kosugi, Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata City 951-8510, Japan. sugishin@med.niigata-u.ac.jp
Telephone: +81-25-2272228 Fax: +81-25-2270779
Received: November 25, 2005
Revised: January 10, 2006
Accepted: January 14, 2006
Published online: July 7, 2006
Revised: January 10, 2006
Accepted: January 14, 2006
Published online: July 7, 2006
Abstract
We here report a case of a 51-year-old man with lung metastasis from esophageal carcinoma that was initially treated by combination chemotherapy consisting of fluorouracil and nedaplatin. Because metastatic disease disappeared, salvage esophagectomy was performed. Although chest wall recurrence developed at the thoracotomy wound, prolonged survival of 48 months was achieved by local tumor resection and additional chemotherapy. This combination chemotherapy is regarded as a promising and considerable treatment for metastatic esophageal carcinoma.
Keywords: Esophageal carcinoma; Lung metastasis; Induction chemotherapy; Fluorouracil; Nedaplatin; Salvage esophagectomy