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World J Gastroenterol. May 28, 2006; 12(20): 3204-3212
Published online May 28, 2006. doi: 10.3748/wjg.v12.i20.3204
Pediatric inflammatory bowel disease
Karen A Diefenbach, Christopher K Breuer
Karen A Diefenbach, Christopher K Breuer, Department of Surgery, Yale University School of Medicine, Division of Pediatric Surgery, 330 Cedar Street, Rm. 132 FMB, North Haven, CT 06520, United States
Author contributions: All authors contributed equally to the work.
Correspondence to: Christopher K Breuer, MD, Department of Surgery, Yale University School of Medicine, Division of Pediatric Surgery, 330 Cedar Street, Rm. 132 FMB, North Haven, CT 06520, United States. christopher.breuer@yale.edu
Telephone: +1-203-7852701 Fax: +1-203-7853820
Received: March 29, 2006
Revised: April 7, 2006
Accepted: April 16, 2006
Published online: May 28, 2006
Abstract

Inflammatory bowel disease is an important cause of gastrointestinal pathology in children and adolescents. The incidence of pediatric inflammatory bowel disease is increasing; therefore, it is important for the clinician to be aware of the presentation of this disease in the pediatric population. Laboratory tests, radiology studies, and endoscopic procedures are helpful in diagnosing inflammatory bowel disease and differentiating between Crohn’s disease and ulcerative colitis. Once diagnosed, the goal of medical management is to induce remission of disease while minimizing the side effects of the medication. Specific attention needs to be paid to achieving normal growth in this susceptible population. Surgical management is usually indicated for failure of medical management, complication, or malignancy. Algorithms for diagnostic evaluation and treatment of pediatric inflammatory bowel disease are presented. The specific psychosocial issues facing these patients are also discussed in this review as are the future goals of research in the complex problem of pediatric inflammatory bowel disease.

Keywords: Pediatric; Inflammatory bowel; Ulcerative colitis; Crohn’s disease