Conventional colonoscopy and magnified chromoendoscopy for the endoscopic histological prediction of diminutive colorectal polyps: A single operator study

doi:10.3748/wjg.v12.i15.2402

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Apr 21, 2006 (publication date) through Apr 28, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 21, 2006; 12(15): 2402-2405
Published online Apr 21, 2006. doi: 10.3748/wjg.v12.i15.2402

Conventional colonoscopy and magnified chromoendoscopy for the endoscopic histological prediction of diminutive colorectal polyps: A single operator study

Giovanni D De Palma, Maria Rega, Stefania Masone, Marcello Persico, Saverio Siciliano, Pietro Addeo, Giovanni Persico

Giovanni D De Palma, Maria Rega, Stefania Masone, Marcello Persico, Saverio Siciliano, Pietro Addeo, Giovanni Persico, Centro di Eccellenza per l’Innovazione Tecnologica in Chirurgia, Dipartimento di Chirurgia Generale e Tecnologie Avanzate, Università degli Studi di Napoli Federico II, Facoltà di Medicina e Chirurgia, Napoli, Italy

Correspondence to: Giovanni D De Palma, DUN Chirurgia Generale e Tecnologie Avanzate, AOU Federico II, Facoltà di Medicina e Chirurgia, Via Pansini, 5, 80131 Napoli, Italy. giovanni.depalma@unina.it

Telephone: +39-81-7462773 Fax: +39-81-8262866

Received: September 2, 2005
Revised: September 20, 2005
Accepted: October 9, 2005
Published online: April 21, 2006

Abstract

AIM: To accurately differentiate the adenomatous from the non-adenomatous polyps by colonoscopy.

METHODS: All lesions detected by colonoscopy were first diagnosed using the conventional view followed by chromoendoscopy with magnification. The diagnosis at each step was recorded consecutively. All polyps were completely removed endoscopically for histological eva-luation. The accuracy rate of each type of endoscopic diagnosis was evaluated, using histological findings as gold standard.

RESULTS: A total of 240 lesions were identified, of which 158 (65.8%) were non-neoplastic and 82 (34.2%) were adenomatous. The overall diagnostic accuracy of conventional view, and chromoendoscopy with magnification was 76.3% (183/240) and 95.4% (229/240), respectively (P < 0.001).

CONCLUSION: The combination of colonoscopy and magnified chromoendoscopy is the most reliable non-biopsy method for distinguishing the non-neoplastic from the neoplastic lesions.

Keywords: Colorectal polyps, Colonoscopy, Chromoen-doscopy, Magnifying endoscopy