Case Report
Copyright ©2005 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 7, 2005; 11(9): 1403-1409
Published online Mar 7, 2005. doi: 10.3748/wjg.v11.i9.1403
Solid-pseudopapillary tumor of the pancreas: Clinical experience and literature review
Hsueh-Lien Huang, Shou-Chuan Shih, Wen-Hsiung Chang, Tsang-En Wang, Ming-Jen Chen, Yu-Jan Chan
Hsueh-Lien Huang, Shou-Chuan Shih, Wen-Hsiung Chang, Tsang-En Wang, Ming-Jen Chen, Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Mackay Medicine Nursing and Management College, Taipei, Taiwan, China
Yu-Jan Chan, Division of Gastroenterology, Department of Pathology, Mackay Memorial Hospital, Mackay Medicine Nursing and Management College, Taipei, Taiwan, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Shou-Chuan Shih, Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, 92, Section 2, Chung-Shan North Road, Taipei, Taiwan, China. yyh1207@yahoo.com.tw
Telephone: +886-225433535-2260
Received: August 18, 2004
Revised: August 20, 2004
Accepted: September 30, 2004
Published online: March 7, 2005
Abstract

AIM: To evaluate the clinical presentations of solid-pseudopapillary tumor of the pancreas (SPT) and examine the diagnosis, treatment, low grade malignant potential of this rare disease.

METHODS: We retrospectively reviewed a series of seven patients with SPT managed in our hospital between July 1990 and October 2003. Six females and one male with mean age of 31 years (range 13 to 50 years) were diagnosed with SPT at our institution.

RESULTS: Clinical presentation included a palpable abdominal mass in two patients and vague abdominal discomfort in another two. Two patients were asymptomatic; their tumors were found incidentally on abdominal sonographic examination for other reasons. The final patient was admitted with hemoperitoneum secondary to tumor rupture. The mean diameter of the tumors in the seven patients was 10.5 cm (range 5 to 20 cm). The lesions were located in the body and tail in five cases and in the head of the pancreas in two. Surgical procedures included distal pancreatectomy (3), distal pancreatectomy with splenectomy (2), pancreaticoduodenectomy (1) and a pylorus-preserving Whipple procedure (1). There were gross adhesions or histological evidence of infiltration to the adjacent pancreas and/or splenic capsule in four cases. None of the patients received adjuvant therapy. The mean follow up was 7 years (range 0.5 to 14 years). One patient developed multiple liver metastases after 14 years of follow up.

CONCLUSION: SPT is a rare tumor that behaves less aggressively than other pancreatic tumor. However, in cases with local invasion, long-term follow up is advisable.

Keywords: Solid-pseudopapillary tumor of the pancreas; Distal pancreatectomy; Pancreaticoduodenectomy