Case Report
Copyright ©2005 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 7, 2005; 11(5): 764-766
Published online Feb 7, 2005. doi: 10.3748/wjg.v11.i5.764
Acquired hepatocerebral degeneration: A case report
Wei-Xing Chen, Ping Wang, Sen-Xiang Yan, You-Ming Li, Chao-Hui Yu, Ling-Ling Jiang
Wei-Xing Chen, Ping Wang, Sen-Xiang Yan, You-Ming Li, Chao-Hui Yu, Ling-Ling Jiang, Department of Gastroenterology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Mr. Ping Wang, Department of Gastroenterology, First Affiliated Hospital, College of Medicine, Zhejiang University, 261 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. structxing@163.com
Telephone: +86-571-87230354 Fax: +86-571-87978444
Received: March 23, 2004
Revised: March 26, 2004
Accepted: April 29, 2004
Published online: February 7, 2005
Abstract

AIM: Acquired hepatocerebral degeneration (AHD) is an exceptional type of hepatic encephalopathies (HE). It is characterized by neuropsychiatric and extrapyramidal symptomathology similar to that seen in hepatolenticular degeneration (Wilson’s disease). In this paper, we report a case of AHD with unusual presenting features.

METHODS: A 28-year-old man with AHD was described and the literature was reviewed.

RESULTS: The man had a history of HBV-related liver cirrhosis. He was admitted to our hospital with apathy, dysarthria, mild consciousness impairment and extrapyramidal symptoms after hematemesis. By review of the literature, cases with AHD often did not present consciousness impairment. So our case was once diagnosed incorrectly as Wilson’s disease.

CONCLUSION: AHD is a rare syndrome and its variable clinical manifestations make it difficult to be diagnosed. But we believe that extensive examination and thorough understanding of the disease are beneficial to a correct diagnosis. Moreover, biocoene is effective in treating the case.

Keywords: Acquired hepatocerebral degeneration