Basic Research
Copyright ©2005 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 28, 2005; 11(4): 521-524
Published online Jan 28, 2005. doi: 10.3748/wjg.v11.i4.521
A non-invasive method for gastrointestinal parameter monitoring
Wen-Xing Wang, Guo-Zheng Yan, Fang Sun, Ping-Ping Jiang, Wen-Qiang Zhang, Gen-Fu Zhang
Wen-Xing Wang, Guo-Zheng Yan, Fang Sun, Ping-Ping Jiang, Wen-Qiang Zhang, Institute of Precision Engineering and Intelligent Microsystem, Shanghai Jiaotong University, Shanghai 200030, China
Gen-Fu Zhang, People’s Hospital of Pudong New District of Shanghai, Shanghai 201200, China
Author contributions: All authors contributed equally to the work.
Supported by the National Natural Science Foundation of China, No. 30270382; High Technology Research and Development Program of China, No. 2002AA404280
Correspondence to: Guo-Zheng Yan, Institute of Precision Engineering and Intelligent Microsystem, Shanghai Jiaotong University, No. 1954, Huashan Road, Shanghai 200030, China. gzhyan@sjtu.edu.cn
Telephone: +86-21-62932821 Fax: +86-21-62933721
Received: December 12, 2003
Revised: December 15, 2003
Accepted: February 1, 2004
Published online: January 28, 2005
Abstract

AIM: To propose a new, non-invasive method for monitoring 24-h pressure, temperature and pH value in gastrointestinal tract.

METHODS: The authors developed a miniature, multi-functional gastrointestinal monitoring system, which comprises a set of indigestible biotelemetry capsules and a data recorder. The capsule, after ingested by patients, could measure pressure, temperature and pH value in the gastrointestinal tract and transmit the data to the data recorder outside the body through a 434 MHz radio frequency data link. After the capsule passed out from the body, the data saved in the recorder were downloaded to a workstation via a special software for further analysis and comparison.

RESULTS: Clinical experiments showed that the biotelemetry capsules could be swallowed by volunteers without any difficulties. The data recorder could receive the radio frequency signals transmitted by the biotelemetry in the body. The biotelemetry capsule could pass out from the body without difficulties. No discomfort was reported by any volunteer during the experiment. In vivo pressure and temperature data were acquired.

CONCLUSION: A non-invasive method for monitoring 24-h gastrointestinal parameters was proposed and tested by the authors. The feasibility and functionality of this method are verified by laboratory tests and clinical experiments.

Keywords: Gastrointestinal monitoring system; pressure; Temperature; Hydrogen Ion Concentration