Brief Reports
Copyright ©The Author(s) 2005. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 21, 2005; 11(27): 4233-4236
Published online Jul 21, 2005. doi: 10.3748/wjg.v11.i27.4233
Effect of autologous blood donation on the central venous pressure, blood loss and blood transfusion during living donor left hepatectomy
Bruno Jawan, Yu-Fan Cheng, Chia-Chi Tseng, Yaw-Sen Chen, Chih-Chi Wang, Tung-Liang Huang, Hock-Liew Eng, Po-Ping Liu, King-Wah Chiu, Shih-Hor Wang, Chih-Che Lin, Tsan-Shiun Lin, Yueh-Wei Liu, Chao-Long Chen
Bruno Jawan, Chia-Chi Tseng, Department of Anesthesiology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Taiwan, China
Yu-Fan Cheng, Yaw-Sen Chen, Chih-Chi Wang, Tung-Liang Huang, Hock-Liew Eng, Po-Ping Liu, King-Wah Chiu, Shih-Hor Wang, Chih-Che Lin, Yueh-Wei Liu, Tsan-Shiun Lin, Chao-Long Chen, Liver Transplantation Program, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Taiwan, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Chao-Long Chen, MD, Superintendent, Chang Gung Memorial Hospital, Ta-pei Road 123, Niao Shung Hsiang, Kaohsiung, Taiwan, China. clchen@adm.cgmh.org.tw
Telephone: +886-7-7317123 Fax: +886-7-7320142
Received: November 18, 2004
Revised: January 1, 2005
Accepted: January 5, 2005
Published online: July 21, 2005
Abstract

AIM: Autologous blood donation (ABD) is mainly used to reduce the use of banked blood. In fact, ABD can be regarded as acute blood loss. Would ABD 2-3 d before operation affect the CVP level and subsequently result in less blood loss during liver resection was to be determined.

METHODS: Eighty-four patients undergoing living donor left hepatectomy were retrospectively divided as group I (GI) and group II (GII) according to have donated 250-300 mL blood 2-3 d before living donor hepatectomy or not. The changes of the intraoperative CVP, surgical blood loss, blood products used and the changes of perioperative hemoglobin (Hb) between groups were analyzed and compared by using Mann-Whitney U test.

RESULTS: The results show that the intraoperative CVP changes between GI (n = 35) and GII (n = 49) up to graft procurement were the same, subsequently the blood loss, but ABD resulted in significantly lower perioperative Hb levels in GI.

CONCLUSION: Since none of the patients required any blood products perioperatively, all the predonated bloods were discarded after the patients were discharged from the hospital. It indicates that ABD in current series had no any beneficial effects, in term of cost, lowering the CVP, blood loss and reduce the use of banked blood products, but resulted in significant lower Hb in perioperative period.

Keywords: Patient; Living donor; Surgery; Hepatectomy; Blood; Autologous; Monitoring; Central venous pressure; Blood loss