Lai CH, Chen HP, Chen TL, Fung CP, Liu CY, Lee SD. Candidal liver abscesses and cholecystitis in a 37-year-old patient without underlying malignancy. World J Gastroenterol 2005; 11(11): 1725-1727 [PMID: 15786561 DOI: 10.3748/wjg.v11.i11.1725]
Corresponding Author of This Article
Dr. Chang-Phone Fung, Section of Infectious Disease, Department of Medicine, Taipei Veterans General Hospital, 201 Shih-Pai Road, Section 2, Taipei 11217, Taiwan, China. laich6363@yahoo.com.tw
Article-Type of This Article
Case Report
Open-Access Policy of This Article
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Chung-Hsu Lai, Hsin-Pai Chen, Section of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, China
Te-Li Chen, Chang-Phone Fung, Cheng-Yi Liu, Section of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, and National Yang-Ming University, Taipei, Taiwan, China
Shou-Dong Lee, Section of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, and National Yang-Ming University, School of Medicine, Taipei, Taiwan, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Chang-Phone Fung, Section of Infectious Disease, Department of Medicine, Taipei Veterans General Hospital, 201 Shih-Pai Road, Section 2, Taipei 11217, Taiwan, China. laich6363@yahoo.com.tw
Telephone: +886-2-28757494 Fax: +886-2-28730052
Received: August 19, 2004 Revised: August 20, 2004 Accepted: October 6, 2004 Published online: March 21, 2005
Abstract
We report a case of candidal liver abscesses and concomitant candidal cholecystitis in a diabetic patient, in whom differences were noted relative to those found in patients with hematologic malignancies. In our case, the proposed entry route of infection is ascending retrograde from the biliary tract. Bile and aspirated pus culture repeatedly tested positive, and blood negative, for Candida albicans and Candida glabrata. Cholecystitis was cured by percutaneous gallbladder drainage and amphotericin B therapy. The liver abscesses were successfully treated by a cumulative dosage of 750 mg amphotericin B. We conclude that in cases involving less immunocompromised patients and those without candidemia, a lower dosage of amphotericin B may be adequate in treating candidal liver abscesses.
